Content

Content - Volume 88, Issue 1

Editor's choice in this issue

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IN THIS ISSUE
In this Issue: Focus on Filaggrin Accumulates: New Swedish Data
Kristian Thestrup-Pedersen
Pages: 3-3
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REVIEW
Congenital Ichthyosis: An Overview of Current and Emerging Therapies
Anders Vahlquist, Agneta Gånemo and Marie Virtanen
Congenital ichthyosis is a collective name for a group of monogenetic disorders of cornification, sometimes associated with systemic symptoms. There may be an abnormal quality or quantity of scale produced, abnormal thickness of stratum corneum or abnormal keratinocyte kinetics, often associated with skin inflammation. Pruri¬tus, skin fragility, ectropion and anhidrosis are sometimes associated w ...
Pages: 4-14
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INVESTIGATIVE REPORT
Loss-of-function Variants of the Filaggrin Gene are Associated with Atopic Eczema and Associated Phenotypes in Swedish Families
Elisabeth Ekelund, Agne Liedén, Jenny Link, Simon P. Lee, Mauro D'Amato, Colin N.A. Palmer, Ingrid Kockum, Maria Bradley
Recent studies have identified 2 loss-of-function variants, R501X and 2282del4, in the filaggrin gene as predisposing factors in the development of eczema. In this study, representing the first analysis of the variants in a Swedish population, we analysed transmission in 406 multiplex eczema families with mainly adult patients. In accordance with previous studies we found association between the f ...
Pages: 15-19
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INVESTIGATIVE REPORT
Burn Injuries and Skin Cancer: A Population-based Cohort Study
Bernt Lindelöf, Britta Krynitz, Fredrik Granath, Anders Ekbom
Development of malignant tumours in chronic burn wounds or scars is extremely rare, but a frequently reported complication. Most of these tumours are squamous cell carcinoma and, more occasionally, basal cell carcinoma and malignant melanoma are reported. The interval between the initial burn and the diagnosis of the tumour is usually long; 20–30 years or more. A large number of case reports and ...
Pages: 20-22
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INVESTIGATIVE REPORT
Bacteriological Study of Epidermal Cysts
Shuichi Kuniyuki, Yuki Yoshida, Naoki Maekawa, Kazuhoshi Yamanaka
The aim of this study was to determine whether bacterial infection plays a significant role in the inflammatory process of epidermal cysts. Samples from 152 patients (115 cases of inflamed and 37 of uninflamed epidermal cysts) were subjected to aerobic and anaerobic bacterial culture and the isolates were investigated. The rate of bacterial growth and the recovered anaerobes were significantly gre ...
Pages: 23-25
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CLINICAL REPORT
Bacterial Skin Infections in Children Hospitalized with Varicella: A Possible Negative Impact of Non-steroidal Anti-inflammatory Drugs?
François Dubos, Valérie Hue, Bruno Grandbastien, Benoît Catteau, Alain Martinot
This 1-year multicentre prospective study in northern France sought to evaluate the incidence of secondary bacterial skin complications related to varicella, describe these superinfections, and analyse risk factors for their onset. The study included every child admitted to a district paediatric unit with a varicella infection. Patients with varicella infection, with and without secondary bacteria ...
Pages: 26-30
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CLINICAL REPORT
Increased Prevalence of Onychomycosis among Psoriatic Patients in Israel
Vera Leibovici, Klilah Hershko, Arieh Ingber, Maria Westerman, Nurit Leviatan-Strauss, Malka Hochberg
Published data on the prevalence of onychomycosis in psoriasis patients compared with healthy controls are controversial, We therefore conducted a prospective study of toenail onychomycosis, among 113 psoriatic and 106 healthy non-psoriatic subjects, selected from the normal population in the Jerusalem area in the period 2003-05. The results revealed a prevalence of 47.6% toenail onychomycosis amo ...
Pages: 31-33
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CLINICAL REPORT
Itch in Primary Biliary Cirrhosis: A Patients’ Perspective
Eric Rishe, Ali Azarm, Nora V. Bergasa
The perception of itch in primary biliary cirrhosis (PBC) is not characterized. Patients with primary biliary cirrhosis who were members of the PBCers Organization were invited to participate in an on-line survey addressing certain characteristics of their itch. Patients used their own words in the questions that asked for descriptions. A total of 238 subjects responded to the survey; of these, 23 ...
Pages: 34-37
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CLINICAL REPORT
Acne Itch: Do Acne Patients Suffer From Itching?
Adam Reich, Katarzyna Trybucka, Anna Tracinska, Dominik Samotij, Blazej Jasiuk, Marek Srama, Jacek C. Szepietowski
Patients with acne often scratch their lesions. As scratch¬ing is also a part of the response to pruritic stimuli, this study aimed to determine whether itching accompanies acne. A total of 108 teenagers (mean age 15.8±1.8 years) with acne were included in the study. All participants completed a specially designed questionnaire on demographic and clinical data. Itching accompanying acne lesions ...
Pages: 38-42
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CLINICAL REPORT
Malignant Transformation of Multiple Familial Trichoepithelioma: Case Report and Literature Review
Kyung Ho Lee, Jung Eun Kim, Baik Kee Cho, Yu Chan Kim and Chul Jong Park
Patients with the autosomal-dominant form of multiple familial trichoepithelioma develop numerous tumours on the face, neck and upper trunk, beginning in childhood. Malignant transformation of such lesions is quite rare; only one case of "malignant trichoepithelioma" has been reported previously, inferring pilomatrix carcinoma on a histological observation. We report here the case of a patient who ...
Pages: 43-46
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CLINICAL REPORT
Conradi-Hünermann-Happle Syndrome (X-linked Dominant Chondrodysplasia Punctata) Confirmed by Plasma Sterol and Mutation Analysis
Annette Kolb-Mäurer, Karl-Heinz Grzeschik, Dorothea Haas, Eva-Bettina Bröcker, Henning Hamm
Conradi-Hünermann-Happle syndrome, or X-linked dominant chondrodysplasia punctata, is a rare genetic disorder characterized by skeletal dysplasia, stippled epiphyses, cataracts, transient ichthyosis and atrophic residua in a mosaic pattern. Mutations in the gene encoding the emopamil-binding protein have been identified as an underlying cause. A 5-year-old girl presented for evaluation of ill-def ...
Pages: 47-51
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CLINICAL REPORT
Multiple Self-healing Squamous Epithelioma of Ferguson-Smith: Observations in a Danish Family Covering Four Generations
Sigurd Broesby-Olsen, Anette Bygum, Anne-Marie Gerdes, Flemming Brandrup
Multiple self-healing squamous epithelioma of Ferguson-Smith (MSSE) is a rare autosomal dominantly inherited disease, almost exclusively reported in patients of Scottish origin, with recurrent, histologically malignant tumours that undergo spontaneous regression. We report clinical observations in a Danish family with 11 affected patients, which appears to be the first Scandinavian family publishe ...
Pages: 52-56
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LETTER TO THE EDITOR
Nail Involvement in Pemphigus Vulgaris
Massimo Carducci, Roberta Calcaterra, Gennaro Franco, Anna Mussi, Claudio Bonifati, Aldo Morrone
This article does not have an abstract.
Pages: 58-60
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LETTER TO THE EDITOR
Reproducibility of Severity Rating for Atopic Dermatitis
Eva Mazzotti, Mauro Paradisi, Alessi Provini, Stefano Tabolli
This article does not have an abstract.
Pages: 60-61
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LETTER TO THE EDITOR
Cinacalcet as First-line Treatment for Calciphylaxis
Valérie Pallure, Christelle Comte, Hélène Leray-Mouragues, Olivier Dereure
This article does not have an abstract.
Pages: 62-63
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LETTER TO THE EDITOR
Single Base Mutation in the Fumarate Hydratase Gene Leading to Segmental Cutaneous Leiomyomatosis
Eva Huter, Noel C. Wortham, Wolfgang Hartschuh, Alexander Enk, Uta Jappe
This article does not have an abstract.
Pages: 63-65
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LETTER TO THE EDITOR
Painful Eye Caused by Basal Cell Carcinoma of the Eyelid: Tumour Enlargement Resulting in Trichiasis
Neil Rajan, Deepali Varma, Fiona Chapman, James A.A. Langtry
This article does not have an abstract.
Pages: 66-66
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LETTER TO THE EDITOR
Three Different Epidermal Naevi With No Organ Involvement: Sebaceous Naevus, Naevus Comedonicus and Becker’s Naevus
Osman Köse, Ercan Çalişkan, Zafer Kurumlu
This article does not have an abstract.
Pages: 67-69
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LETTER TO THE EDITOR
Eosinophilic Granulomatous Reaction after Intradermal Injection of Hyaluronic Acid
Shuko Okada, Ryuhei Okuyama, Hachiro Tagami and Setsuya Aiba
This article does not have an abstract.
Pages: 69-70
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LETTER TO THE EDITOR
Malar Lichen Planus: A New Variant
Nawaf Al-Mutairi, Arun Joshi
This article does not have an abstract.
Pages: 71-72
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LETTER TO THE EDITOR
Dialysis-related Amyloidosis on the Buttocks
Kaoru Takayama, Takahiro Satoh, Ryuji Maruyama, Hiroo Yokozeki
This article does not have an abstract.
Pages: 72-73
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LETTER TO THE EDITOR
Combination of Low-dosage Cyclosporine and Topical Pimecrolimus in Severe Atopic Dermatitis with Chronic Hepatitis B
Elena Campione, Evelin Jasmine Paternò, Laura Diluvio, Luca Bianchi, Giammarco Giorgetti, Sergio Chimenti
This article does not have an abstract.
Pages: 74-75
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LETTER TO THE EDITOR
Pyoderma Gangrenosum-like Primary Cutaneous Cryptococcosis
Kim Ch. Jasch, Barbara Hermes, Uta Scheller, Wolfgang Harth
This article does not have an abstract.
Pages: 76-77
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LETTER TO THE EDITOR
Chronic Urticaria and Angioedema with Concomitant Eosinophilic Vasculitis due to Trichinella Infection
Regina Renner, Anne Fleck, Stefan Schubert, R. Christoph Baerwald, Jörg Beer, Ralf Schober, Konstanze Holl-Ulrich, Michael Sticherling
This article does not have an abstract.
Pages: 78-79
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LETTER TO THE EDITOR
Acute Urticaria Associated with Amoeboid Forms of Blastocystis sp. Subtype 3
Alexandra Katsarou-Katsari, Constantine M. Vassalos, Konstantina Tzanetou, Gregory Spanakos, Chryssanthy Papadopoulou, Nicholas Vakalis
This article does not have an abstract.
Pages: 80-81
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LETTER TO THE EDITOR
Reactive Eccrine Syringofibroadenomatosis Associated with Venous Stasis and Plaque Psoriasis
Hong Liang Tey, Suat Hoon Tan
This article does not have an abstract.
Pages: 82-84
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LETTER TO THE EDITOR
Cetuximab-induced Acneiform Eruption and the Response to Isotretinoin
Pamela Vezzoli, Angelo Valerio Marzano, Franceso Onida, Elvio Alessi, Barbara Galassi, Maurizio Tomirotti, Emilio Berti
This article does not have an abstract.
Pages: 84-86
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LETTER TO THE EDITOR
Subacute Cutaneous Lupus Erythematosus Induced or Exacerbated by Proton Pump Inhibitors
Claus Dam, Anette Bygum
This article does not have an abstract.
Pages: 87-89
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LETTER TO THE EDITOR
Outcome of "Short-term" Dead Sea Climatotherapy for Psoriasis
Arnon D. Cohen, Jonathan Shapiro, David Michael, Emmilia Hodak, Dina Van-Dijk, Lechaim Naggan, Daniel A. Vardy
This article does not have an abstract.
Pages: 90-91
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LETTER TO THE EDITOR
Collision of Pigmented Benign Tumours: A Possible Simulator of Melanoma
M. Carmen González-Vela, J. Fernando Val-Bernal, Marcos A. González-López, Mariona Novell, J. Héctor Fernández-Llaca
This article does not have an abstract.
Pages: 92-93
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