Content

Content - Volume 92, Issue 6

Editors choice in this issue

INVESTIGATIVE REPORT
Melanocortin 1 Receptor (MC1R) Variants in High Melanoma Risk Patients are Associated with Specific Dermoscopic ABCD Features
Koen D. Quint, Jasper I. van der Rhee, Nelleke A. Gruis, Jeanet A. ter Huurne, Ron Wolterbeek, Nienke van der Stoep, Wilma Bergman, Nicole A. Kukutsch
Individuals with two red hair colour (RHC)-MC1R genetic variants have light skin and blond/reddish hair and, in comparison with those without such alleles, are at an increased risk of developing melanoma. Our study investigated the association of RHC variants and the Total Dermo-scopy Score (TDS), and the items that make up the TDS, in those with atypical naevi and melanomas from high risk melanom ...
Pages: 587-592
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CLINICAL REPORT
Warts in a Cohort of Danish Kidney Transplanted Patients: Impact on Quality of Life
Claus Zachariae, Carsten Sand, Jesper Melchior Hansen, Søren Schwartz Sørensen, Karen Koch, John Villumsen, Mads Axelsen
There are no published clinical studies evaluating the impact of warts on quality of life after transplantation. The aim of this study was to determine the frequency of self-reported skin warts and skin cancer and their impact on quality of life in kidney transplanted patients, as measured with the Dermatology Life Quality Index (DLQI). Of 740 patients with a functioning renal allograft and were f ...
Pages: 615-618
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INVESTIGATIVE REPORT
Lifestyle and Nickel Allergy in a Swedish Adolescent Population: Effects of Piercing, Tattooing and Orthodontic Appliances
Ronny Fors, Maurits Persson, Erik Bergström, Hans Stenlund, Birgitta Stymne, Berndt Stenberg
The aim of this study was to estimate the prevalence of life­style practices in adolescents and their association with nickel allergy. Upper secondary school pupils (n = 4,376; 15–23 years) were patch-tested for nickel aller­gy, follow­ing completion of a questionnaire (answered by 6,095). Almost 86% girls and 21% of boys reported piercing. More girls (6%) than boys (3%) had ...
Pages: 664-668
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All articles

IN THIS ISSUE
Commentary I: Skin Cancer: Clear Skies Sometimes Help
Jonathan L. Rees, Lisa Naysmith
Abstract is missing
Pages: 585-586
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IN THIS ISSUE
Commentary II: The Void of Congenital Naevi
Wilma Bergman, K. Gmelig Meijling
Abstract is missing
Pages: 586-586
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INVESTIGATIVE REPORT
Melanocortin 1 Receptor (MC1R) Variants in High Melanoma Risk Patients are Associated with Specific Dermoscopic ABCD Features
Koen D. Quint, Jasper I. van der Rhee, Nelleke A. Gruis, Jeanet A. ter Huurne, Ron Wolterbeek, Nienke van der Stoep, Wilma Bergman, Nicole A. Kukutsch
Individuals with two red hair colour (RHC)-MC1R genetic variants have light skin and blond/reddish hair and, in comparison with those without such alleles, are at an increased risk of developing melanoma. Our study investigated the association of RHC variants and the Total Dermo-scopy Score (TDS), and the items that make up the TDS, in those with atypical naevi and melanomas from high risk melanom ...
Pages: 587-592
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INVESTIGATIVE REPORT
Kinesin Family Member 20A is a Novel Melanoma-associated Antigen
Junji Yamashita, Satoshi Fukushima, Masatoshi Jinnin, Noritoshi Honda, Katunari Makino, Keisuke Sakai, Shinichi Masuguchi, Yuji Inoue, Hironobu Ihn
It has been shown recently that immunotherapy for advanced melanoma is effective. However, in order to improve the efficacy of immunotherapy, the identification of more specific melanoma-associated antigens is urgently needed. Kinesin family member 20A (KIF20A) has been reported to be a promising immunotherapeutic target for pancreatic cancer. To investigate the expression of KIF20A in melanoma, w ...
Pages: 593-597
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CLINICAL REPORT
Coping Strategies in Melanoma Patients
Michael Trapp, Eva-Maria Trapp, Erika Richtig, Josef Wilhelm Egger, Anna Zampetti, Francesca Sampogna, Peter Michael Rohrer, Peter Komericki, Tanja Strimitzer, Michael Dennis Linder
An observational, questionnaire-based, cross-sectional study was performed to assess whether differences in coping behaviour (positive and negative strategies) between patients with either a recent diagnosis of malignant melanoma (MM) or with benign dermatological disease, were predictive of the diagnosis. Coping strategies were assessed with the German version of the stress-coping questionnaire ( ...
Pages: 598-602
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LETTER TO THE EDITOR
Acquired Agminated Melanocytic Naevi: Report of Two Cases and Review of the Literature
Yasumasa Shimasaki, Yukie Fukuta, Yuichi Yoshida, Hiromi Higaki-Mori, Osamu Yamamoto
Abstract is missing (Letter)
Pages: 603-604
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LETTER TO THE EDITOR
Rapidly Involuting Congenital Melanocytic Naevi in Two Children
Iara Trocoli Drakensjö, Mari-Anne Hedblad, Carl-Fredrik Wahlgren
Abstract is missing (Letter)
Pages: 605-606
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LETTER TO THE EDITOR
Melanoma in a 5-year-old Child with a Giant Congenital Melanocytic Naevus
Tiziana Surrenti, Andrea Diociaiuti, Alessandro Inserra, Antonella Accinni, Loredana Giraldi, Francesco Callea, May El Hachem
Abstract is missing (letter)
Pages: 607-608
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INVESTIGATIVE REPORT
No Association between Infections, HLA Type and Other Transplant-related Factors and Risk of Cutaneous Squamous Cell Carcinoma in Solid Organ Transplant Recipients
Åsa Ingvar, Karin Ekström Smedby, Bernt Lindelöf, Pia Fernberg, Rino Bellocco, Gunnar Tufveson, Petter Höglund, Johanna Adami
Recipients of solid organ transplants are at a markedly increased risk of cutaneous squamous cell carcinoma (SCC). We investigated potential associations between post-transplant infections, HLA type, and other transplant-related factors and risk of SCC, taking immuno­suppressive treatment into account. A population-based case-control study was conducted. All patients who developed SCC during foll ...
Pages: 609-614
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CLINICAL REPORT
Warts in a Cohort of Danish Kidney Transplanted Patients: Impact on Quality of Life
Claus Zachariae, Carsten Sand, Jesper Melchior Hansen, Søren Schwartz Sørensen, Karen Koch, John Villumsen, Mads Axelsen
There are no published clinical studies evaluating the impact of warts on quality of life after transplantation. The aim of this study was to determine the frequency of self-reported skin warts and skin cancer and their impact on quality of life in kidney transplanted patients, as measured with the Dermatology Life Quality Index (DLQI). Of 740 patients with a functioning renal allograft and were f ...
Pages: 615-618
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LETTER TO THE EDITOR
Splicing Aberration in Naevoid Basal Cell Carcinoma Syndrome
Yosuke Ishitsuka, Junichi Furuta, Toshiyuki Miyashita, Fujio Otsuka
Abstract is missing (Letter)
Pages: 619-620
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LETTER TO THE EDITOR
Twist1 as a Possible Biomarker for Metastatic Basal Cell Carcinoma
Yuta Majima, Satoshi Hirakawa, Yukiko Kito, Hiroki Suzuki, Masayo Koide, Hidekazu Fukamizu, Yoshiki Tokura
Abstract is missing (Letter)
Pages: 621-622
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LETTER TO THE EDITOR
Quantification of Plasmacytoid Dendritic Cells and Type 1 Myeloid Dendritic Cells in Peripheral Blood of Renal Transplant Recipients With and Without Squamous Cell Carcinoma
Lene F. Sandvik, Petra Vogelsang, Torbjørn Leivestad, Roland Jonsson, Silke Appel
Abstract is missing (letter)
Pages: 623-624
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INVESTIGATIVE REPORT
Comparison of Foxp3+ Regulatory T cells and CD163+ Macrophages in Invasive and Non-invasive Extramammary Paget’s Disease
Taku Fujimura, Yumi Kambayashi, Takanori Hidaka, Akira Hashimoto, Takahiro Haga, Setsuya Aiba
Regulatory T cells (Tregs), identified by the expression of CD4, CD25 and Foxp3, together with immunosuppressive macrophages, such as CD163+ M2 macrophages, are involved in maintaining peripheral tolerance. The aim of this study was to elucidate the involvement of Tregs and CD163+ macrophages in invasive and non-invasive extramammary Paget’s disease. The presence of CD4+CD25+Foxp3+ Tregs, CD163+ ...
Pages: 625-628
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LETTER TO THE EDITOR
Cutaneous Myeloid Sarcoma Presenting as Grey Pigmented Macules
Shiro Niiyama, Yasuyuki Amoh, Akira Watarai, Kensei Katsuoka, Hideki Mukai
Abstract is missing (Letter)
Pages: 629-630
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LETTER TO THE EDITOR
CD163+ Adult Xanthogranuloma Arising from Merkel Cell Carcinoma Treated with Local Radiotherapy
Ryoko Shimada, Taku Fujimura, Yumi Kambayashi, Tomoyuki Ohtani, Mei Nasu, Yukikazu Numata, Takahiro Haga, Akira Hashimoto, Setsuya Aiba
Abstract is missing (letter)
Pages: 631-632
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LETTER TO THE EDITOR
Importance of Genetic Studies in Patients with Multiple Merkel Cell Carcinomas
Iris Ahronowitz, Paul Nghiem, Siegrid Yu
Abstract is missing (Letter)
Pages: 633-634
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LETTER TO THE EDITOR
Incidental Gastric Signet-ring Cell Carcinoma Metastasis to the Skin in Basal Cell Carcinoma
Yasuhiro Nakamura, Kaishi Satomi, Masayuki Noguchi, Michiko Shibata-Ito, Yasuhiro Fujisawa, Yasuhiro Kawachi, Fujio Otsuka
Abstract is missing (letter)
Pages: 635-636
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LETTER TO THE EDITOR
Extranodal T-cell/Histiocyte-rich Large B-cell Lymphoma Presenting Primarily on the Skin
Yumi Kambayashi, Taku Fujimura, Akira Tsukada, Akira Hashimoto, Setsuya Aiba
Abstract is missing (Letter)
Pages: 637-639
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LETTER TO THE EDITOR
Cutaneous Lymphangitis Carcinomatosis Metastasis of Extra-ovarian Primary Peritoneal Carcinoma
Satoshi Nakamura, Yoshio Hashimoto, Kaoru Nishi, Toshihiro Mizumoto, Hidetoshi Takahashi, Hajime Iizuka
Abstract is missing (Letter)
Pages: 639-640
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INVESTIGATIVE REPORT
Light Fractionation Significantly Improves the Response of Superficial Basal Cell Carcinoma to Aminolaevulinic Acid Photodynamic Therapy: Five-year Follow-up of a Randomized, Prospective Trial
Hannah C. de Vijlder, Henricus J.C.M. Sterenborg, H.A. Martino Neumann, Dominic J. Robinson, Ellen R.M. de Haas
Photodynamic therapy (PDT) using topical porphyrin-precursors is a promising treatment for superficial basal cell carcinoma (sBCC), but it needs further optimization. The aim of this study was to compare 5-year lesion (complete) response rates of sBCC treated with topical aminolaevulinic acid (ALA)-PDT using a single illumination vs. ALA-PDT using a 2-fold illumination scheme. A prospective, rando ...
Pages: 641-647
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CLINICAL REPORT
Successful Treatment of Multiple Basaliomas with Bleomycin-based Electrochemotherapy: A Case Series of Three Patients with Gorlin-Goltz Syndrome
Erika Kis, Eszter Baltás, Ágnes Kinyó, Erika Varga, Nikoletta Nagy, Rolland Gyulai, Lajos Kemény, Judit Oláh
Gorlin-Goltz syndrome is a rare multisystemic disease, characterized by numerous basal cell carcinomas. The ideal approach for patients with the syndrome would be a treatment with a high cure rate, minimal scarring, short healing time and mild side-effects. Electrochemo­therapy is a novel therapeutic option that ablates tumours with electrical current and simultaneously administered anticancer dr ...
Pages: 648-651
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LETTER TO THE EDITOR
Daylight Photodynamic Therapy in Private Practice in Switzerland: Gain Without Pain
Lasse R. Braathen
Abstract is missing (Letter)
Pages: 652-653
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LETTER TO THE EDITOR
Successful Treatment of HER-2-Positive Metastatic Apocrine Carcinoma of the Skin with Lapatinib and Capecitabine
Takanori Hidaka, Taku Fujimura, Akiko Watabe, Akira Hashimoto, Takahiro Haga, Kaoru Onami, Masato Mizuashi, Setsuya Aiba
Abstract is missing (Letter)
Pages: 654-655
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LETTER TO THE EDITOR
Successful Treatment of Buschke-Lowenstein Tumour of the Penis with Carbon Dioxide Laser Vaporization
Jean Ayer, Sarah Matthews, Nick Francis, Neil P.J. Walker, M. Dinneen, Christopher B. Bunker
Abstract is missing (Letter)
Pages: 656-657
Abstract  PDF
LETTER TO THE EDITOR
Successful Treatment of Pigmented Dermatofibrosarcoma Protuberance on the Nasal Root with CyberKnife Radiosurgery
Takanori Hidaka, Taku Fujimura, Akira Hashimoto, Setsuya Aiba
Abstract is missing (Letter)
Pages: 658-659
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LETTER TO THE EDITOR
Successful Treatment of Bowen’s Disease with Topical Maxacalcitol
Tadashi Karashima, Keiko Hashikawa, Fumitake Ono, Hironobu Eguchi, Takahiro Hamada, Norito Ishii, Teruki Dainichi, Shinichiro Yasumoto, Daisuke Tsuruta, Takashi Hashimoto
Abstract is missing (Letter)
Pages: 660-661
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Book Reviews
Pages: 662-663
Abstract  PDF
INVESTIGATIVE REPORT
Lifestyle and Nickel Allergy in a Swedish Adolescent Population: Effects of Piercing, Tattooing and Orthodontic Appliances
Ronny Fors, Maurits Persson, Erik Bergström, Hans Stenlund, Birgitta Stymne, Berndt Stenberg
The aim of this study was to estimate the prevalence of life­style practices in adolescents and their association with nickel allergy. Upper secondary school pupils (n = 4,376; 15–23 years) were patch-tested for nickel aller­gy, follow­ing completion of a questionnaire (answered by 6,095). Almost 86% girls and 21% of boys reported piercing. More girls (6%) than boys (3%) had ...
Pages: 664-668
Abstract  HTML  PDF
INVESTIGATIVE REPORT
Sequencing-based Molecular Typing of Treponema pallidum Strains in the Czech Republic: All Identified Genotypes are Related to the Sequence of the SS14 Strain
Magdalena Flasarová, Petra Pospíšilová, Lenka Mikalová, Zuzana Vališová, Elika Dastychová, Radim Strnadel, Ivana Kuklová, Vladana Woznicová, Hana Zákoucká, David Šmajs
A set of 415 clinical samples isolated from 294 patients suspected of having syphilis collected in the Czech Republic between 2004 and 2010 was tested for the presence of treponemal DNA. Standard serological tests showed that 197 patients were syphilis-seropositive and 97 patients were syphilis-seronegative. In each sample, PCR tests for polA (TP0105), tmpC (TP0319), TP0136, TP0548 and 23S rRNA ge ...
Pages: 669-674
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INVESTIGATIVE REPORT
Light-emitting Diodes at 830 and 850 nm Inhibit Melanin Synthesis In vitro
Jeong Mo Kim, Nan-Hyung Kim, Yu Shun Tian, Ai Young Lee
Treatment of hyperpigmentation remains a challenge. Because of the positive effects of low-energy Nd:YAG lasers on the treatment of melasma, it is suggested that laser-like light-emitting diodes (LEDs) can potentially ameliorate hyperpigmentation. We evaluated the effect of seven different LED wavelengths on melanogenesis. LED irradiation at 830 nm (dose-dependent, from 1 to 20 J/cm2) and 850 nm ( ...
Pages: 675-680
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CLINICAL REPORT
Erythema Nodosum-like Lesions in Behçet’s Disease: A Clinicopatho­logical Study of 26 Cases
Noriyuki Misago, Yoshifumi Tada, Syuichi Koarada, Yutaka Narisawa
The histopathological features of erythema nodosum-like lesions remain controversial with regard to whether they resemble those of conventional erythema nodosum. We reviewed the clinicopathological features of erythema nodosum-like lesions in 26 patients with Behçet’s disease and evaluated the clinical characteristics of Behçet’s disease in these patients. The results suggest that: (i) the c ...
Pages: 681-686
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CLINICAL REPORT
Eccrine Poromatosis Associated with Polychemotherapy
Kazuyasu Fujii, Seiko Aochi, Chinatsu Takeshima, Masaki Ohtsuka, Toshihisa Hamada, Kenji Asagoe, Yumi Aoyama, Shin Morizane, Keiji Iwatsuki
Eccrine poroma frequently occurs as a solitary tumour, and only a few reports have described the occurrence of multiple lesions. Multiple eccrine poromas, or eccrine poromatosis, may occur in patients who have undergone radiotherapy and/or polychemotherapy. We report here four cases of multiple eccrine poromas in patients who were either undergoing, or had undergone, intensive chemotherapy (from 6 ...
Pages: 687-690
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LETTER TO THE EDITOR
Acquired Dermal Melanocytosis Induced by Psoralen Plus Ultraviolet A Therapy
Kotaro Nagase, Noriyuki Hirashima, Shinichi Koba, Takuya Inoue, Noriyuki Misago, Yutaka Narisawa
Abstract is missing (Letter)
Pages: 691-692
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LETTER TO THE EDITOR
Time-course of the Change in Titre of Antibodies Against Type VII Collagen in a Patient with Epidermolysis Bullosa Acquisita
Mika Sato, Asako Ishitsuka, Yoshiano Shibuya, Hiroyuki Kanoh, Hiroshi Koga, Takashi Hashimoto, Mariko Seishima
Abstract is missing (letter)
Pages: 693-694
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LETTER TO THE EDITOR
Enamel Defects in Carriers of a Novel LAMA3 Mutation Underlying Epidermolysis Bullosa
Wing Yan Yuen, Anna M.G. Pasmooij, Cornelis Stellingsma, Marcel F. Jonkman
Abstract is missing (Letter)
Pages: 695-696
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