Content

Content - Volume 93, Issue 2

Editor's choice in this issue

REVIEW
A Comprehensive Pathophysiology of Dandruff and Seborrheic Dermatitis – Towards a More Precise Definition of Scalp Health
James R. Schwartz, Andrew G. Messenger, Antonella Tosti, Gail Todd, Maria Hordinsky, Roderick J. Hay, Xuemin Wang, Claus Zachariae, Kathy M. Kerr, James P. Henry, Rene C. Rust, Michael K. Robinson
Despite an increasing knowledge of dandruff and seborrheic dermatitis (D/SD), the pathophysiological understanding is still incomplete but suggests a role of Malassezia yeasts in triggering inflammatory and hyper-proliferative epidermal responses. The objective of this report is to review published literature from in vivo studies of D/SD populations to provide a more complete description of overal ...
Pages: 131-137
Abstract  HTML  PDF
INVESTIGATIVE REPORT
Association of Nerve Growth Factor, Chemokine (C-C motif) Ligands and Immunoglobulin E with Pruritus in Cutaneous T-cell Lymphoma
Hiraku Suga, Makoto Sugaya, Tomomitsu Miyagaki, Hanako Ohmatsu, Hideki Fujita, Shinji Kagami, Yoshihide Asano, Yayoi Tada, Takafumi Kadono, Shinichi Sato
Many patients with cutaneous T-cell lymphoma (CTCL) experience severe pruritus. This study evaluated serum levels of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) in patients with CTCL. Although serum NGF and BDNF levels in patients with CTCL were not significantly higher than in healthy controls, serum NGF levels in patients with Sézary syndrome were higher than in those ...
Pages: 144-149
Abstract  HTML  PDF
Theme: Venereology: Not To Be Forgotten
Seventeen articles icluded. For example: Awareness of HPV Infection, Genitoanal Warts and Cancer in Dermatological Outpatients.Association of Autoimmune Diseases with Lichen Sclerosus in 532 Male and Female Patients
Pages: 216-255
Abstract  PDF

All articles

REVIEW
A Comprehensive Pathophysiology of Dandruff and Seborrheic Dermatitis – Towards a More Precise Definition of Scalp Health
James R. Schwartz, Andrew G. Messenger, Antonella Tosti, Gail Todd, Maria Hordinsky, Roderick J. Hay, Xuemin Wang, Claus Zachariae, Kathy M. Kerr, James P. Henry, Rene C. Rust, Michael K. Robinson
Despite an increasing knowledge of dandruff and seborrheic dermatitis (D/SD), the pathophysiological understanding is still incomplete but suggests a role of Malassezia yeasts in triggering inflammatory and hyper-proliferative epidermal responses. The objective of this report is to review published literature from in vivo studies of D/SD populations to provide a more complete description of overal ...
Pages: 131-137
Abstract  HTML  PDF
INVESTIGATIVE REPORT
Stratum Corneum Drying Drives Vertical Compression and Lipid Organization and Improves Barrier Function In vitro
Ichiro Iwai, Naomi Kunizawa, Eiichiro Yagi, Tetsuji Hirao, Ichiro Hatta
The stratum corneum dehydrates after exogenous hydration due to skincare or bathing. In this study, sheets of stratum corneum were isolated from reconstructed human epidermis and the barrier function and structure of these sheets were assessed during drying with the aim of improving our understanding of skincare. Water diffusion through the sheets of stratum corneum decreased with drying, accompan ...
Pages: 138-143
Abstract  PDF
INVESTIGATIVE REPORT
Association of Nerve Growth Factor, Chemokine (C-C motif) Ligands and Immunoglobulin E with Pruritus in Cutaneous T-cell Lymphoma
Hiraku Suga, Makoto Sugaya, Tomomitsu Miyagaki, Hanako Ohmatsu, Hideki Fujita, Shinji Kagami, Yoshihide Asano, Yayoi Tada, Takafumi Kadono, Shinichi Sato
Many patients with cutaneous T-cell lymphoma (CTCL) experience severe pruritus. This study evaluated serum levels of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) in patients with CTCL. Although serum NGF and BDNF levels in patients with CTCL were not significantly higher than in healthy controls, serum NGF levels in patients with Sézary syndrome were higher than in those ...
Pages: 144-149
Abstract  HTML  PDF
INVESTIGATIVE REPORT
IL-20, IL-21 and p40: Potential Biomarkers of Treatment Response for Ustekinumab
Anne Gedebjerg, Claus Johansen, Knud Kragballe, Lars Iversen
Although biological drugs in psoriasis treatment show clinical efficacy, there are still a proportion of patients in whom little treatment response is obtained. The aim of this study was to identify molecular biomarkers for treatment response and to investigate the molecular effects of ustekinumab treatment of psoriasis. The mRNA expression of various genes in skin biopsies was analysed by quantit ...
Pages: 150-155
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INVESTIGATIVE REPORT
Co-existence of Chronic Urticaria and Metabolic Syndrome: Clinical Implications
Young-Min Ye, Hyun-Jung Jin, Eui-Kyung Hwang, Young-Hee Nam, Joo-Hee Kim, Yoo-Seob Shin, Hae-Sim Park
A systemic pro-inflammatory and pro-coagulating state occurs in subjects who have both chronic urticaria and metabolic syndrome. To investigate the prevalence and clinical impact of metabolic syndrome in Korean patients with chronic urticaria, a hospital-based cross-sectional study of 131 patients was performed. Metabolic syndrome was assessed by the criteria of the National Cholesterol Education ...
Pages: 156-160
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INVESTIGATIVE REPORT
Role of Small Intestinal Bacterial Overgrowth and Helicobacter pylori Infection in Chronic Spontaneous Urticaria: A Prospective Analysis
Anna Campanati, Rosaria Gesuita, Melania Giannoni, Francesca Piraccini, Lucia Sandroni, Emanuela Martina, Luca Conocchiari, Emanuele Bendia, Antonio Di Sario, Annamaria Offidani
The aim of this study is to assess the associations between chronic spontaneous urticaria (CSU), Helicobacter pylori infection and small intestinal bacterial overgrowth. Forty- eight patients with CSU were studied by scoring the urticaria activity and assesing the quality of life. Patients with H. pylori infection (n = 11) or small intestinal bacterial overgrowth (n = 13) ...
Pages: 161-164
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CLINICAL REPORT
Cutaneous Manifestations of Helicobacter cinaedi Infection
Satoko Shimizu, Daisuke Inokuma, Mika Watanabe, Toshiya Sakai, Satoshi Yamamoto, Kikuo Tsuchiya, Hiroshi Shimizu
Helicobacter cinaedi causes gastroenteritis and bacter-aemia, particularly in immunocompromised individuals. Although cellulitis is sometimes reported to accompany infection by this pathogen, the cutaneous manifestations are poorly understood. To clarify the characteristic cutaneous features, 47 cases of H. cinaedi bacteraemia experienced at Sapporo City General Hospital as nosocomial infection we ...
Pages: 165-167
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CLINICAL REPORT
Can On-demand Non-sedating Antihistamines Improve Urticaria Symptoms? A Double-blind, Randomized, Single-dose Study
Karsten Weller, Elena Ardelean , Elisabeth Scholz , Peter Martus, Torsten Zuberbier, Marcus Maurer
Non-sedating H1-antihistamines are the recommended first-line treatment for chronic spontaneous urticaria. While efficacy studies usually apply continuous daily treat-ment regimens, many patients take their medication on demand. In this randomized, double-blind trial we tested whether on-demand H1-antihistamine desloratadine in standard and higher doses is able to improve the resolution of existin ...
Pages: 168-174
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CLINICAL REPORT
Effective Control of Recalcitrant Pruritus by Bevacizumab: A Possible Role for Vascular Endothelial Growth Factor in Chronic Itch?
Karoline Krause, Clemens Krull, Birgit Kessler, Bernhard Lange-Asschenfeldt, Marcus Maurer, Martin Metz
Prurigo is a difficult to treat condition characterized by severe pruritus presenting with chronic secondary scratch lesions. We report here a dramatic improvement in pruritus in a patient with prurigo simplex who was being treated with bevacizumab, a monoclonal vascular endothelial growth factor (VEGF) antibody. On the basis of the increased VEGF expression measured in the skin of this patient, s ...
Pages: 175-179
Abstract  HTML  PDF
LETTER TO THE EDITOR
Clearance Efficacy of Autoantibodies in Double Filtration Plasmapheresis for Pemphigus Foliaceus
Akira Kasuya, Mutsumi Moriki, Kazuki Tatsuno, Satoshi Hirakawa, Yoshiki Tokura
Abstract is missing (Letter)
Pages: 181-182
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LETTER TO THE EDITOR
Inflammed Skin Harbours Th9 Cells
Chiara Cortelazzi, Nicoletta Campanini, Roberto Ricci, Giuseppe De Panfilis
Abstract is missing (Letter)
Pages: 183-185
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LETTER TO THE EDITOR
No Basophil Infiltration in Alopecia Areata Irrespective of the Intensity of Eosinophil Infiltration
Sachiko Ono, Atsushi Otsuka, Yoshiki Miyachi, Kenji Kabashima
Abstract is missing (Letter)
Pages: 185-186
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LETTER TO THE EDITOR
Cryptococcal Cellulitis in a Patient with Bullous Pemphigoid
Kazumitsu Sugiura, Nana Sugiura, Tetsuya Yagi, Mitsutaka Iguchi, Hideaki Ohno, Yoshitsugu Miyazaki, Masashi Akiyama
Abstract is missing (Letter)
Pages: 187-188
Abstract  HTML  PDF
LETTER TO THE EDITOR
Gouty Panniculitis also Involving the Bone Marrow
Chang-Min Choi, Bark-Lynn Lew, Sang-Ho Lee, Woo-Young Sim
Abstract is missing (Letter)
Pages: 189-190
Abstract  HTML  PDF
LETTER TO THE EDITOR
Cutaneous Serratia marcescens Infection in an Immunocompetent Patient after Filler Injection
Kui Young Park, Seong Jun Seo
Abstract is missing (Letter)
Pages: 191-192
Abstract  HTML  PDF
LETTER TO THE EDITOR
Cutaneous Disseminated Sporotrichosis Complicated by Osteomyelitis
Karen E. Eustace, Felipe M.S. Sampaio, Marcelo R. Lyra, Leonardo Quintella, Antonio C.F. do Valle
Abstract is missing (Letter)
Pages: 192-193
Abstract  HTML  PDF
LETTER TO THE EDITOR
Novel Mutation in GJB4 Gene (Connexin 30.3) in a Family with Erythrokeratodermia Variabilis
Emilie Sbidian, Norredine Bousseloua, Laurence Jonard, Stéphanie Leclerc-Mercier, Christine Bodemer, Smail Hadj-Rabia
Abstract is missing (Letter)
Pages: 193-195
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LETTER TO THE EDITOR
Chronic Unilateral Facial Ulcer Revealing Wegener’s Granulomatosis in a Patient with Rheumatoid Arthritis
Zhe Guo, Yi Liu, Song Zheng, Li Qiu, Jian Wu, Ting Xiao
Abstract is missing (Letter)
Pages: 196-197
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LETTER TO THE EDITOR
Extensive Chronic Tuberculosis luposa Treated Incorrectly with Long-term Course of Isoniazid Monotherapy
Ewa Plomer-Niezgoda, Anita Hryncewicz-Gwóźdź, Robert Gołąb, Piotr Pluciński, Joanna Maj, Zdzisław Woźniak, Alina Jankowska-Konsur
Abstract is missing (Letter)
Pages: 198-199
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LETTER TO THE EDITOR
Concurrent Cytomegalovirus and Herpes Simplex Virus Infection in Pemphigus Vulgaris Treated with Rituximab and Prednisolone
Hsien-Yi Chiu, Chia-Ying Chang, Cheng-Hsiang Hsiao, Li-Fang Wang
Abstract is missing (Letter)
Pages: 200-201
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LETTER TO THE EDITOR
Confluent and Reticulated Papillomatosis Associated with 15q Tetrasomy Syndrome
Hanako Koguchi, Hideyuki Ujiie, Satoru Aoyagi, Rinko Osawa, Hiroshi Shimizu
Abstract is missing (Letter)
Pages: 202-203
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LETTER TO THE EDITOR
Cutaneous Amyloid Elastosis Revealing Multiple Myeloma with Systemic Amyloidosis
Angélique Marchand , Xavier Levaltier , Anne Croué , Brigitte Arbeille, Norbert Ifrah , Ludovic Martin
Abstract is missing (Letter)
Pages: 204-205
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LETTER TO THE EDITOR
Long-term Treatment of Severe Recalcitrant Atopic Dermatitis with Omalizumab, an Anti-immuno-globulin E
Sven R. Quist, Andreas Ambach, Daniela Göppner, Jennifer Quist, Ingolf Franke, Bernd Bonnekoh, Harald P. M. Gollnick
Abstract is missing (Letter)
Pages: 206-208
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LETTER TO THE EDITOR
Recurrent Erythema Annulare Centrifugum During Ustekinumab Treatment in a Psoriatic Patient
Wei-Ting Chou, Tsen-Fang Tsai
Abstract is missing (Letter)
Pages: 208-209
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LETTER TO THE EDITOR
Some Observations on Reporting Quality of Life in Treatment of Psoriasis in Outpatient Clinics
Magnus Lindberg, Mats Berg
Abstract is missing (letter)
Pages: 210-211
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LETTER TO THE EDITOR
Toxic Epidermal Necrolysis with Some Features of Acute Generalized Exanthematous Pustulosis
Takahiro Kiyohara, Takahiro Sawai, Hideki Ido, Masanobu Kumakiri
Abstract is missing (Letter)
Pages: 212-214
Abstract  HTML  PDF
LETTER TO THE EDITOR
Verbalizing Extremes of the Visual Analogue Scale for Pruritus: A Consensus Statement
Masutaka Furue, Toshiya Ebata, Akihiko Ikoma, Satoshi Takeuchi, Yoko Kataoka, Kenji Takamori, Takahiro Satoh, Hidehisa Saeki, Matthias Augustin, Adam Reich, Jacek Szepietowski, Alan Fleischer, Christine Blome, Ngoc Quan Phan, Elke Weisshaar, Gil Yosipovitch, Sonja Ständer
Abstract is missing (Letter)
Pages: 214-215
Abstract  HTML  PDF
Theme: Venereology: Not To Be Forgotten
Seventeen articles icluded. For example: Awareness of HPV Infection, Genitoanal Warts and Cancer in Dermatological Outpatients.Association of Autoimmune Diseases with Lichen Sclerosus in 532 Male and Female Patients
Pages: 216-255
Abstract  PDF
CLINICAL REPORT
Awareness of Human Papillomavirus Infection, Genitoanal Warts and Cancer in a Dermatological Outpatient Clinic Setting
Laura Kuznetsov, Christina M. Reitmaier-Weber, Thomas Ruzicka, Alexander V. Kuznetsov
There has been little research into awareness of human papillomavirus (HPV) among dermatological out-patients, despite the fact that management of HPV infection causing genitoanal warts/cancer is part of the routine practice of dermato-venereologists. The aim of this study was to explore awareness of HPV among dermatological outpatients. A self-administered questionnaire was distributed to 360 co ...
Pages: 218-222
Abstract  HTML  PDF
INVESTIGATIVE REPORT
The Spectrum of Genital Human Papillomavirus Infection Among Men Attending a Swedish Sexually-transmitted Infections Clinic: Human Papillomavirus Typing and Clinical Presentation of Histopathologically Benign Lesions
Arne Wikström, Ismini Vassilaki, Mari-Anne Hedblad, Stina Syrjänen
There have been a number of Swedish studies on human papillomavirus (HPV) typing in men, most of which have used less sensitive HPV-typing techniques. The present study included male patients with genital HPV-induced lesions planned for surgery. Samples were prepared for histopathology and PCR. HPV was detected in 233/253 (92%) and HPV 6 or 11 in 89% of the HPV-positive lesions. There were statist ...
Pages: 223-227
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LETTER TO THE EDITOR
Bowenoid Papulosis and Invasive Bowen’s Disease: A Multidisciplinary Approach
Elena Campione, Chiara Centonze, Laura Diluvio, Augusto Orlandi, Cesidio Cipriani, Alessandro Di Stefani, Emilio Piccione, Sergio Chimenti, Luca Bianchi
Abstract is missing (Letter)
Pages: 228-229
Abstract  HTML  PDF
CLINICAL REPORT
Clinical and Microscopic Signs of Cervicitis and Urethritis: Correlation with Chlamydia trachomatis Infection in Female STI Patients
Matilda Berntsson, Petra Tunbäck
Chlamydia trachomatis is among the most prevalent genital infections and is an important cause of tubal factor infertility. The majority of infected females are asymptomatic. Evidence on the reliability of signs of inflammation used to predict chlamydia in female patients is inconsistent. This study examined associations between criteria routinely used in many Scandinavian sexually transmitted inf ...
Pages: 230-233
Abstract  HTML  PDF
LETTER TO THE EDITOR
Three Episodes of Brain Stroke as a Manifestation of Neurosyphilis in an HIV-infected Man
Małgorzata Inglot, Anna Szymanek, Aleksandra Szymczak, Weronika Rymer, Tomasz Pawłowski, Przemysław Pacan, Jacek C. Szepietowski
Abstract is missing (Letter)
Pages: 234-235
Abstract  HTML  PDF
LETTER TO THE EDITOR
Secondary Syphilis with Persisting Hard Chancre on the Forearm
Pedro Andrade, Maria J. Juliao, José P. Reis, Américo Figueiredo
Abstract is missing (Letter)
Pages: 236-237
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CLINICAL REPORT
Association of Autoimmune Diseases with Lichen Sclerosus in 532 Male and Female Patients
Alexander Kreuter, Yulia Kryvosheyeva, Sarah Terras, Rose Moritz, Katrin Möllenhoff , Peter Altmeyer, Nina Scola, Thilo Gambichler
Lichen sclerosus is a relatively common chronic inflammatory skin disease that predominantly affects the anogenital area. Accumulating evidence indicates that lichen sclerosus in women may be associated with other autoimmune disease, whereas this association seems to lack in male patients. We retrospectively evaluated the prevalence of autoimmune diseases and serological parameters indicative for ...
Pages: 238-241
Abstract  HTML  PDF
CLINICAL REPORT
Characterization of Vulvar Skin of Healthy Thai Women: Influence of Sites, Age and Menopause
Tsutomu Fujimura, Noriko Sato, Suwirakorn Ophaswongse, Yutaka Takagi, Mitsuyuki Hotta, Takashi Kitahara, Yoshinori Takema, Piti Palungwachira
Although the physiological characteristics of vulvar skin have been characterized in Caucasians, little is known about the vulvar skin of Asian women. This study assessed the moisture content, transepidermal water loss (TEWL) and pH of vulvar skin of 99 healthy Asian women residing in Bangkok, aged 20–69 years, during their non-menstrual period, including 39 post-menopausal women. Skin pH was ac ...
Pages: 242-245
Abstract  HTML  PDF
LETTER TO THE EDITOR
Urinary Voiding Symptomatology (Micro-incontinence) in Male Genital Lichen Sclerosus
Chris B. Bunker, Neil Patel, Tang N. Shim
Abstract is missing (letter)
Pages: 246-248
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LETTER TO THE EDITOR
Penile Erosions as First Manifestation of Pemphigus Vulgaris: A Misleading Presentation
Marco Stieger, Nedzmidin Pelivani, Albert-Adrien Ramelet, Helmut Beltraminelli, Luca Borradori
Abstract is missing (Letter)
Pages: 248-249
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QUIZ
Ulcerated Nodules on the Oral Mucosa and Fingers: A Quiz
Nina Booken, Markus Heck, Wiebke K. Peitsch, Sergij Goerdt, Claus-Detlev Klemke
Abstract is missing (Quiz)
Pages: 250-252
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QUIZ
Solitary Lesion on Finger: A Quiz
Enrico Streit, Wolfgang Hartschuh, Katharina Flux
Abstract is missing (Quiz)
Pages: 250-253
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QUIZ
Nodular Lesions on Post-surgical Scars: A Quiz
Federica Scarfi, Meena Arunachalam, Massimiliano Galeone , Elisa Difonzo
Abstract is missing (Quiz)
Pages: 251-254
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QUIZ
A Brownish Verrucous Plaque on the Intergluteal Cleft: A Quiz
Joon Soo Park, In Yong Kim, In Soo Chae, Dong Kyun Ko, Hyun Chung
Abstract is missing (Quiz)
Pages: 251-254
Abstract  HTML  PDF