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Content - Volume 94, Issue 2

Editors choice in this issue

CLINICAL REPORT
Factors Associated with Remission of Eczema in Children: A Population-based Follow-up Study
Laura B. von Kobyletzki, Carl-Gustaf Bornehag, Elizabeth Breeze, Malin Larsson, Cecilia Boman Lindström, Åke Svensson
The aim of this study was to analyse factors associated with remission of atopic dermatitis (AD) in childhood. A population-based AD cohort of 894 children aged 1–3 years from a cross-sectional baseline study in 2000 was followed up in 2005. The association between remission, background, health, lifestyle, and environmental variables was estimated with crude and multivariable logistic regression ...
Pages: 179-184
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INVESTIGATIVE REPORT
Shiny White Streaks: A Sign of Malignancy at Dermoscopy of Pigmented Skin Lesions
Danielle Shitara, Priscila Ishioka , Yarel Alonso-Pinedo, Leyla Palacios-Bejarano, Cristina Carrera, Josep Malvehy, Susana Puig
The aim of this study was to evaluate the practical importance of the presence of shiny white streaks (SWS) (chrysalis or crystalline structures in polarized dermoscopy) for suspicion of malignancy, diagnosis of melanoma, and pre-operative estimation of Breslow thickness and its correlation with total dermoscopy score (TDS). SWS were present in 13.6% of 800 consecutive excised lesions. The presenc ...
Pages: 132-137
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INVESTIGATIVE REPORT
Referrals by General Practitioners for Suspicious Skin Lesions: The Urgency of Training
Margit C.J. van Rijsingen, Sabine C.A. Hanssen, Joannes M.M. Groenewoud, Gert Jan van der Wilt, Marie-Jeanne P. Gerritsen
Skin cancer is common among white populations and rapid increases in incidence are being observed in many countries, leading to a large burden on healthcare systems. Unnecessary referrals from general practitioners (GPs) may contribute to this burden. The aim of this study was to analyse the quality of referrals from GPs of patients with skin tumours. Referral letters for 734 patients were collect ...
Pages: 138-141
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All articles

IN THIS ISSUE
Predictors of Early Remission in Atopic Dermatitis
Kristian Thestrup-Pedersen
Page: 131
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INVESTIGATIVE REPORT
Shiny White Streaks: A Sign of Malignancy at Dermoscopy of Pigmented Skin Lesions
Danielle Shitara, Priscila Ishioka , Yarel Alonso-Pinedo, Leyla Palacios-Bejarano, Cristina Carrera, Josep Malvehy, Susana Puig
The aim of this study was to evaluate the practical importance of the presence of shiny white streaks (SWS) (chrysalis or crystalline structures in polarized dermoscopy) for suspicion of malignancy, diagnosis of melanoma, and pre-operative estimation of Breslow thickness and its correlation with total dermoscopy score (TDS). SWS were present in 13.6% of 800 consecutive excised lesions. The presenc ...
Pages: 132-137
Abstract  HTML  PDF
INVESTIGATIVE REPORT
Referrals by General Practitioners for Suspicious Skin Lesions: The Urgency of Training
Margit C.J. van Rijsingen, Sabine C.A. Hanssen, Joannes M.M. Groenewoud, Gert Jan van der Wilt, Marie-Jeanne P. Gerritsen
Skin cancer is common among white populations and rapid increases in incidence are being observed in many countries, leading to a large burden on healthcare systems. Unnecessary referrals from general practitioners (GPs) may contribute to this burden. The aim of this study was to analyse the quality of referrals from GPs of patients with skin tumours. Referral letters for 734 patients were collect ...
Pages: 138-141
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INVESTIGATIVE REPORT
Association of 25-hydroxyvitamin D with Metabolic Syndrome in Patients with Psoriasis: A Case-control Study
Jacinto Orgaz-Molina, César Magro-Checa, Miguel A. Arrabal-Polo, Enrique Raya-Álvarez, Ramón Naranjo, Agustin Buendía-Eisman , Salvador Arias-Santiago
Vitamin D deficiency is associated with higher cardiovascular risk and metabolic syndrome (MeS) criteria. The main objective of this study was to analyse the association of 25-hydroxyvitamin D (25-OHD) serum levels with MeS (National Cholesterol Education Program–Adult Treatment Panel-III criteria) in 46 Spanish patients with psoriasis, but without arthritis and systemic treatment, and 46 contro ...
Pages: 142-145
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INVESTIGATIVE REPORT
Narrow-band Ultraviolet B Treatment Boosts Serum 25-hydroxyvitamin D in Patients with Psoriasis on Oral Vitamin D Supplementation
Meri J. Ala-Houhala, Toni Karppinen, Katja Vähävihu, Hannu Kautiainen, Yvonne Dombrowski, Erna Snellman, Jürgen Schauber, Timo Reunala
A course of treatment with narrow-band ultraviolet B (NB-UVB) improves psoriasis and increases serum 25-hydroxyvitamin D (25(OH)D). In this study 12 patients with psoriasis who were supplemented with oral cholecalciferol, 20 µg daily, were given a course of NB-UVB and their response measured. At baseline, serum 25(OH)D was 74.14 ± 22.9 nmol/l. At the 9th exposure to NB-UVB 25(OH)D ha ...
Pages: 146-151
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INVESTIGATIVE REPORT
Acceptance and Usability of Different Sunscreen Formulations among Outdoor Workers: A Randomized, Single-blind, Cross-over Study
Andrea Bauer, Kathrin Hault, Andrea Püschel, Henriette Rönsch, Peter Knuschke, Stefan Beissert
Adequate sun protection is often neglected during occupational outdoor work. To investigate the acceptance and usability of sunscreens during outdoor work a single-blind, randomized-controlled, cross-over trial was performed in 40 subjects. Two sunscreen formulations were used daily on working days for 4 weeks at a time, with a wash-out phase before crossover. The primary outcome was overall accep ...
Pages: 152-156
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CLINICAL REPORT
Serum Angiopoietin-like Protein 3 Levels: Possible Correlation with Progressive Skin Sclerosis, Digital Ulcers and Pulmonary Vascular Involvement in Patients with Systemic Sclerosis
Yohei Ichimura, Yoshihide Asano, Kaname Akamata, Naohiko Aozasa, Shinji Noda, Takashi Taniguchi, Takehiro Takahashi, Tetsuo Toyama, Hayakazu Sumida, Yosihiro Kuwano, Koichi Yanaba, Yayoi Tada, Makoto Sugaya, Shinichi Sato, Takafumi Kadono
Angiopoietin-like protein 3 (ANGPTL3), which is part of a family of secreted glycoproteins that are structurally similar to angiopoietins, is principally expressed in the liver and is involved in lipid metabolism and angiogenesis. The aim of this study was to determine the clinical significance of serum ANGPTL3 levels, measured with a specific enzyme-linked immunosorbent assay, in patients with sy ...
Pages: 157-162
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INVESTIGATIVE REPORT
Characteristics and Provision of Care in Patients with Chronic Hand Eczema: Updated Data from the CARPE Registry
Christian Apfelbacher, Sonja Molin, Elke Weisshaar, Andrea Bauer, Peter Elsner, Vera Mahler, Melanie Weiss, Thomas Ruzicka, Thomas L. Diepgen
The aim of the CARPE registry is to investigate characteristics and medical care in patients affected by chronic hand eczema. Patients are assessed by dermatological examination and patient questionnaire. Socio-economic and clinical data are collected, and quality of life is measured using the Dermatology Life Quality Index (DLQI). A total of 1,163 patients with chronic hand eczema were eligible f ...
Pages: 163-167
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INVESTIGATIVE REPORT
Increased Density of Cutaneous Nerve Fibres in the Affected Dermatomes After Herpes Zoster Therapy
Charalampos Zografakis, Dina G. Tiniakos, Marina Palaiologou, Mirsini Kouloukoussa, Christos Kittas, Nikos Staurianeas
Herpes zoster neural injury was assessed by determining cutaneous nerve density in skin biopsies from the affected dermatomes of 35 adult patients with herpes zoster in the acute phase and 3 months post-treatment, using protein gene product 9.5 immunohistochemistry. In contrast to the significant increase in subepidermal nerve fibre density (11.77 ± 4.88/mm vs. 13.29 ± 5. ...
Pages: 168-172
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INVESTIGATIVE REPORT
CD11c+ Dendritic Cells Rather than Langerhans Cells are Reduced in Normal Skin of Immunosuppressed Renal Transplant Recipients
Lene F. Sandvik, Kathrine Skarstein, Lisbet Sviland, Einar Svarstad, Arvid E. Nilsen, Torbjørn Leivestad, Roland Jonsson, Silke Appel
The increased risk of squamous cell carcinomas (SCC) in renal transplant recipients (RTR) is related to impaired immunosurveillance as a consequence of immunosuppressive therapy. Since dendritic cells (DC) play an important role in immunosurveillance, we investigated the quantity of DC subsets and macrophages in normal skin of RTR and immunocompetent controls by immunohistochemistry. In this compa ...
Pages: 173-178
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CLINICAL REPORT
Factors Associated with Remission of Eczema in Children: A Population-based Follow-up Study
Laura B. von Kobyletzki, Carl-Gustaf Bornehag, Elizabeth Breeze, Malin Larsson, Cecilia Boman Lindström, Åke Svensson
The aim of this study was to analyse factors associated with remission of atopic dermatitis (AD) in childhood. A population-based AD cohort of 894 children aged 1–3 years from a cross-sectional baseline study in 2000 was followed up in 2005. The association between remission, background, health, lifestyle, and environmental variables was estimated with crude and multivariable logistic regression ...
Pages: 179-184
Abstract  HTML  PDF
CLINICAL REPORT
Adult Atopic Dermatitis Patients and Physical Exercise: A Swedish Questionnaire Study
Sol-Britt Lonne-Rahm, Isabelle Sundström, Klas Nordlind, Lars-Magnus Engström
Physical activity promotes health and prevents disease. When patients with atopic dermatitis (AD) undertake exercise, the itch often gets worse due to sweating, and this may reduce their engagement in physical exercise. The aim of this study was to determine the level of physical exercise in patients with AD compared with a control group from a normal population. Our hypothesis was that patients w ...
Pages: 185-187
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CLINICAL REPORT
Self-reported Skin Diseases, Quality of Life and Medication Use: A Nationwide Pharmaco-epidemiological Survey in Sweden
Magnus Lindberg, Dag Isacson, Kerstin Bingefors
The aim of this study was to determine self-reported consumption of dermatological pharmaceuticals and quality of life (QoL), measured with Short Form 36, in relation to eczema, acne, psoriasis and other inflammatory skin conditions in the Swedish population. A questionnaire containing questions on the occurrence of skin diseases, health-related QoL and the use of pharmaceuticals was sent to a cro ...
Pages: 188-191
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CLINICAL REPORT
Effectiveness of Interdisciplinary vs. Dermatological Care of Moderate- to-severe Psoriasis: A Pragmatic Randomised Controlled Trial
Jochen Schmitt, Gottfried Wozel, Marlene Garzarolli, Antje Viehweg, Michael Bauer, Karolina Leopold
Psychiatric morbidity is frequent in patients with psoriasis. We compared the effectiveness of dermatological vs. interdisciplinary dermatological and psychiatric care for psoriasis. Adults with moderate-to-severe psoriasis were randomly allocated to dermatological (n = 24) or interdisciplinary care (n = 23) and treated accordingly. Primary endpoint was the mean change in D ...
Pages: 192-197
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CLINICAL REPORT
Reliability, Responsiveness and Validity of Scalpdex in Children with Scalp Psoriasis: The Dutch Study
Annet M. Oostveen, Elke M.G.J. de Jong, Andrea W.M. Evers, A. Rogier T. Donders, Peter C.M. van de Kerkhof, Marieke M.B. Seyger
This aim of this study was to validate the Scalpdex, a quality of life questionnaire for adults with scalp dermatitis, in children with scalp psoriasis. The reliability, responsiveness and validity of the 3 scales (symptoms, functioning and emotions) of this 22-item questionnaire were analysed in a cohort of children with scalp psoriasis (age range 6–18 years). A total of 94 children completed t ...
Pages: 198-202
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CLINICAL REPORT
Clinical Significance of Anti-desmoglein-1 and -3 Circulating Autoantibodies in Pemphigus Patients Measured by Area Index and Intensity Score
Aikaterini Patsatsi, Aikaterini Kyriakou, Anastasia Giannakou, Aikaterini Pavlitou-Tsiontsi, Alexandros Lambropoulos, Dimitrios Sotiriadis
Detection of anti-desmoglein-1 (anti-DSG-1) and anti-DSG-3 autoantibodies is widely used in the diagnosis of pemphigus. Two validated scoring systems, Pemphigus Disease Area Index (PDAI) and Autoimmune Bullous Skin Disorder Intensity Score (ABSIS), are used for the evaluation of clinical severity. The aim of this cross-sectional study was to interpret the titres of pemphigus autoantibodies in corr ...
Pages: 203-206
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CLINICAL REPORT
Prevalence of Human Papillomavirus in Anal and Oral Sites Among Patients with Genital Warts
Kristian Kofoed, Carsten Sand, Ola Forslund, Klaus Madsen
Genital warts are caused by human papillomavirus (HPV). HPV is a leading cause of anogenital malignancies and a role of HPV in the aetiology of oro-pharyngeal cancers has been demonstrated. The frequency of oral HPV infection in patients with genital warts and the association between concomitant genital, anal and oral infection is unclear. A total of 201 men and women with genital wart-like lesion ...
Pages: 207-211
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CLINICAL REPORT
Orf Virus Infection in a Hunter in Western Austria, Presumably Transmitted by Game
Maria Kitchen, Hansgeorg Müller, Alexandra Zobl, Andrea Windisch , Nikolaus Romani, Hartwig Huemer
A variety of animals host parapoxviruses. Orf virus is prevalent in sheep and goats in the Tyrol region of Austria and Northern Italy. Zoonotic infections in humans mostly occur after occupational exposure. We report here a case of a hunter with a typical Orf lesion (contagious ecthyma) on the finger, with no history of direct contact with domestic animals. Three weeks previously he had been hunti ...
Pages: 212-214
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CLINICAL REPORT
Tumescent Suction Curettage vs. Curettage Only for Treatment of Axillary Hyperhidrosis Evaluated by Subjective and New Objective Methods
Christian Tronstad, Per Helsing, Kim Alexander Tønseth, Sverre Grimnes, Anne Lene Krogstad
The main purpose of this study was to compare the effect of the 2 minimally invasive surgical techniques for treating axillary hyperhidrosis: superficial tumescent suction curettage and curettage only. A total of 22 patients diagnosed with axillary hyperhidrosis received one type of treatment at each side, randomized. Examinations were performed pre-operatively and at 3, 6 and 12 months following ...
Pages: 215-220
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SHORT COMMUNICATION
Eosinophilic Fasciitis following Allogeneic Bone Marrow Transplantation in a Patient with Acute Myeloid Leukaemia
Gong-Yao Chu, Hsing-Lin Lin, Gwo-Shing Chen, Ching-Ying Wu
Abstract is missing (Short)
Pages: 221-222
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SHORT COMMUNICATION
Generalized Granulomatous Dermatitis Accompanied by Myelodysplastic Syndrome
Akiko Hagiwara, Taku Fujimura, Sadanori Furudate, Yumi Kambayashi, Yukikazu Numata, Takahiro Haga, Setsuya Aiba
Abstract is missing (Short)
Pages: 223-224
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SHORT COMMUNICATION
Localized Cutaneous Amyloidosis Associated with Poikilodermatous Mycosis Fungoides
Kentaro Izumi, Ken Arita, Keita Horie, Daichi Hoshina, Hiroshi Shimizu
Abstract is missing (Short)
Pages: 225-226
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SHORT COMMUNICATION
Neurolymphomatosis Associated with Erythrodermic Mycosis Fungoides
Satoshi Ogawa, Atsushi Fukunaga, Mami Kanata, Ayuko Kikuzawa, Toshinori Bito, Yoshihisa Otsuka, Kenji Sekiguchi, Nobuyuki Oka, Chikako Nishigori
Abstract is missing (Short)
Pages: 227-228
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SHORT COMMUNICATION
Overlap of IgA Pemphigus and Linear IgA Dermatosis in a Patient with Ulcerative Colitis: A Mere Coincidence?
Johannes S. Kern, Wolfgang Gehring, Wolfgang Kreisel, Michael Hertl, Kristin Technau-Hafsi, Leena Bruckner-Tuderman, Silke C. Hofmann
Abstract is missing (Short)
Pages: 228-230
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SHORT COMMUNICATION
Detection of Apoptotic Keratinocytes in a Case of Bullous Pemphigoid Developed after Graft-versus-host Disease
Kozo Yoneda, Toshio Demitsu, Maki Kakurai, Tae Narita, Kozo Nakai, Yasuo Kubota, Norito Ishii, Takashi Hashimoto
Abstract is missing (Short)
Pages: 231-232
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SHORT COMMUNICATION
A Case of Mycosis Fungoides with Large Cell Transformation Associated with Infliximab Treatment
Hiraku Suga, Makoto Sugaya, Tetsuo Toyama, Hayakazu Sumida, Hideki Fujita, Asako Kogure, Atsuyuki Igarashi, Shinichi Sato
Abstract is missing (Short)
Pages: 233-234
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SHORT COMMUNICATION
IgA Paraneoplastic Pemphigus in Angioimmunoblastic T-cell Lymphoma with Antibodies to Desmocollin 1, Type VII Collagen and Laminin 332
Mika Yashiro, Toshiaki Nakano, Tomonori Taniguchi, Kensei Katsuoka, Noriyuki Tadera, Koji Miyazaki, Kwesi Teye, Hiroshi Koga, Takashi Hashimoto
Abstract is missing (Short)
Pages: 235-236
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SHORT COMMUNICATION
A Case of Mucous Membrane Pemphigoid Involving the Trachea and Bronchus with Autoantibodies to β3 Subunit of Laminin-332
Kohei Kato, Yoshihiro Moriyama, Hiroaki Saito, Hiroshi Koga, Takashi Hashimoto
Abstract is missing (Short)
Pages: 237-238
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SHORT COMMUNICATION
Digital Vasculitis with Eosinophilia Possibly Associated with Etanercept Therapy
Kyoko Nakahigashi, Gyohei Egawa, Yoshiki Miyachi, Kenji Kabashima
Abstract is missing (Short)
Pages: 239-240
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SHORT COMMUNICATION
Cryotherapy Caused Widespread Subcutaneous Emphysema Mimicking Angiooedema
Peter Jensen, Urs B. Johansen, Jacob P. Thyssen
Abstract is missing (Short)
Pages: 241-241
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SHORT COMMUNICATION
Combination Therapy with Amphotericin-B and Miltefosine for Post-kala-azar Dermal Leishmaniasis: A Preliminary Report
Venkat Ramesh , Kumar Avishek, Vanila Sharma, Poonam Salotra
Abstract is missing (Short)
Pages: 242-243
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SHORT COMMUNICATION
Urticarial Vasculitis Associated with Essential Thrombocythaemia
Annabel D. Scott, Nicholas Francis , Helen Yarranton , Sarita Singh
Abstract is missing (Short)
Pages: 244-245
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SHORT COMMUNICATION
Atypical Presentation of Genital Herpes Simplex (HSV-2) in Two Patients with Chronic Lymphocytic Leukemia
Tang N. Shim, Suks Minhas, Asif Muneer, Christopher B. Bunker
Abstract is missing (Short)
Pages: 246-247
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SHORT COMMUNICATION
Multidisciplinary Approach to Pyemotes ventricosus Papular Urticaria Dermatitis
Monica Corazza, Massimo Tassinari, Marco Pezzi, Michela Ricci, Alessandro Borghi, Sara Minghetti, Marilena Leis
Abstract is missing (Short)
Pages: 248-249
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SHORT COMMUNICATION
Effective Oral Psoralen Plus Ultraviolet A Therapy for Digital Ulcers with Revascularization in Systemic Sclerosis
Tomoko Inoue, Toshifumi Yamaoka, Hiroyuki Murota, Akinori Yokomi , Atsushi Tanemura, Ken Igawa, Mamori Tani, Ichiro Katayama
Abstract is missing (Short)
Pages: 250-251
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BOOK REVIEW
Adverse Cutaneous Drug Eruptions
Maria Bradley
Page: 252
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QUIZ
Pain and Hyperpigmentation of the Toes: A Quiz
Felipe Maurício Soeiro Sampaio, Vitor Ribeiro Gomes de Almeida Valviesse, Julia Ocampo Lyra-da-Silva, Emerson Cicilini Mesquita, Luciana Gomes Pedro Brandão, Antonio Carlos Francesconi do Valle
Abstract is missing (Quiz)
Pages: 253-256
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QUIZ
A Solitary Ulcer of the Tongue: A Quiz
Manuraj Singh, Giuseppe Ficarra, Domenico Tesi , Daniela Massi, Catherine M. Stefanato
Abstract is missing (Quiz)
Pages: 253-256
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QUIZ
A Segmental Rash in a Young Male: A Quiz
Eirini E. Merika, Christopher B. Bunker, Nicholas Francis , Sarita Singh
Abstract is missing (Quiz)
Pages: 253-256
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