Content » Vol 96, Issue 5

Clinical Report

Cost-utility Analysis of Supported Self-management with Motiva­tional Interviewing for Patients with Psoriasis

Marie H. Larsen, Astrid K. Wahl, Anne-Lene Krogstad, Eline Aas
DOI: 10.2340/00015555-2331


There are few studies evaluating the cost-effectiveness of self-management interventions for patients with psoriasis. Motivational interviewing (MI) as a telephone follow-up after climate-heliotherapy was effective on several clinical parameters, but its cost-effectiveness is unknown. A cost-utility analysis was conducted alongside a randomized controlled trial (RCT) comparing MI with usual care. A total of 169 Norwegian patients were included. A within-trial analysis compared the costs and quality-adjusted life years (QALYs). Utilities were measured with the 15D instrument, supplemented with Dermatological Life Quality Index (DLQI). A time-integrated summary score defined the clinical effects. QALYs were adjusted for baseline differences. MI provided equivalent quality of life and utility (15D: –0.0022 QALYs (95% Cl –0.02, 0.01), p=0.77, and DLQI: –0.62 QALYs (95%CI –0.65, 0.41), p=0.24, at lower costs €–1103 (–2293, 87), p=0.058, compared with treatment-as-usual. The MI intervention was thus cost-effective. This result was more evident when using the DLQI as outcome measure compared with 15D.


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