Content » Vol 96, Issue 5

Clinical Report

Comparison of 5-Aminolevulinic Acid Photodynamic Therapy and Clobetasol Propionate in Treatment of Vulvar Lichen Sclerosus

Lei Shi, Fei Miao, Ling-Lin Zhang, Guo-Long Zhang, Pei-Ru Wang, Jie Ji, Xiao-Jie Wang, Zheng Huang, Hong-Wei Wang, Xiu-Li Wang
DOI: 10.2340/00015555-2341


The aim of this study was to evaluate the effectiveness of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) for the treatment of vulvar lichen sclerosus (VLS) and compare its effectiveness with that of clobetasol propionate. Four sessions of topical photodynamic therapy (PDT) were administered at 2-week intervals (n?=?20). Clobetasol propionate (0.05%) was used daily for 8 weeks (n?=?20). The rate of complete response in the PDT group (14/20) was double that of the clobetasol propionate group (7/20) (p?


Supplementary content


Not logged in! You need to login/create an account to comment on articles. Click here to login/create an account.