Content

Content - Volume 83, Issue 2

All articles

Porphyria Cutanea Tarda Still much to be learnt
This article does not have an abstract.
Page: 81
Abstract  PDF
MMPs: They are there and they do something - also in Dermatology
Torbjörn Egelrud
This article does not have an abstract.
Pages: 81-82
Abstract  PDF
LETTER TO THE EDITOR
Production of Retroviral Vectors in Primary Human Keratinocytes after DNA-Mediated Gene Transfer Leads to Prolonged Gene Expression
THOMAS G. JENSEN, UFFE B. JENSEN, LARS BOLUND
Prolonged stability and controlled expression of gene constructs transferred directly to human skin improve the possibility of using this tissue in somatic gene therapy. We aim to develop a simple transfection method resulting in retroviral mediated gene transfer to keratinocyte stem cells in situ. We here show that after DNA-mediated gene transfer into primary human keratinocytes it is pos ...
Pages: 83-87
Abstract  PDF
LETTER TO THE EDITOR
The Vulva Skin Microclimate: Influence of Panty Liners on Temperature, Humidity and pH
BO RUNEMAN , GÖRAN RYBO A3, OLLE LARKÖ A2, JAN FAERGEMANN A2
Many women use panty liners between menstrual periods. The aim of this study was to investigate whether the use of such products might influence the vulva skin. Twelve healthy women were studied on four occasions with three different product constructions and on one occasion without products. Temperature, surface wetness and surface pH were measured on vulva skin. Mean skin temperature when the wo ...
Pages: 88-92
Abstract  PDF
LETTER TO THE EDITOR
Effect of a Moisturizer on Skin Susceptibility to NiCl2
CLAUS ZACHARIAE A1, ELISABETH HELD A1, JEANNE DUUS JOHANSEN A1, TORKIL MENNÉ A1, TOVE AGNER A1
The aim of this study was to evaluate whether a moisturizer used on normal skin can increase skin response to allergens. Twelve nickel-allergic volunteers applied a lipid-rich moisturizer on the upper arm 3 times daily for 7 days, while the other upper arm served as a control. A control group followed the same treatment protocol. Following treatment with moisturizer, patch tests with 1% NiCl
Pages: 93-97
LETTER TO THE EDITOR
Expression of p53 in Normal Sun-exposed and Protected Skin (Type IV-V) in Different Decades of Age
MOETAZ BELLAH EL-DOMYATI A1, SAMEH ATTIA A1, FATMA SALEH A1, NOREEN GALARIA A2, HESHAM AHMAD , FRANCES P. GASPARRO A2, JOUNI UITTO A2
The checkpoint protein p53, which is activated by DNA damage, is involved in the decision whether the cells should stop replication and proceed to repair their DNA or die by apoptosis. We evaluate the expression of p53 and the number of apoptotic cells in normal sun-exposed (face) and protected (abdomen) skin in Egyptians between 6 and 77 years of age. The degree of p53 expression in facial skin s ...
Pages: 98-104
Abstract  PDF
LETTER TO THE EDITOR
Matrix Metalloproteinases-2 and -9 are Secreted from Human Fibroblasts
TAKASHI KOBAYASHI A1, SHUNJI HATTORI A2, HIROSHI SHINKAI A1
To investigate the pathophysiological role of fibroblasts in tissue metabolism, we analysed gelatin-degrading enzymes secreted from skin cells in culture. Using a gelatin-zymography method, matrix metalloproteinase (MMP)-2 was constitutively secreted from fibroblasts, whereas both MMP-2 and MMP-9 were secreted from keratinocytes. MMP-9 expression by fibroblasts was induced by the addition of tr ...
Pages: 105-107
Abstract  PDF
LETTER TO THE EDITOR
Matrix Metalloproteinase-19 is Expressed by Keratinocytes in Psoriasis
SARI SUOMELA A2, ARJA-LEENA KARINIEMI A3, ULLA IMPOLA A2, SEIJA-LIISA KARVONEN A4, ERNA SNELLMAN A5, TUTTA UURASMAA A6, JUHA PELTONEN A7, ULPU SAARIALHO-KERE A2
Keratinocyte hyperproliferation, inflammatory infiltrates, neoangiogenesis and alterations in cytokine levels are hallmarks of psoriatic skin. Matrix metalloproteinases (MMPs) have been associated with the remodeling of the extracellular matrix during inflammation, neovascularization, and malignant transformation. We have previously shown that particularly MMP-12 is abundantly expressed by macroph ...
Pages: 108-114
Abstract  PDF
LETTER TO THE EDITOR
Familial and Sporadic Porphyria Cutanea Tarda: Clinical, Biochemical and Genetic Features with Emphasis on Iron Status
ANETTE BYGUM A2, LENE CHRISTIANSEN A3, NIELS ERIK PETERSEN A3, MOGENS HØRDER A3, KRISTIAN THOMSEN A4, FLEMMING BRANDRUP A2
The manifestation of porphyria cutanea tarda reflects genetic and environmental factors. Mutations in the uroporphyrinogen decarboxylase gene, located at chromosome 1p34, discriminate familial porphyria cutanea tarda from sporadic cases. Furthermore, mutations in the haemochromatosis gene may be involved in the aetiology. In this study 53 unrelated Danish patients with porphyria cutanea tarda were ...
Pages: 115-120
Abstract  PDF
LETTER TO THE EDITOR
Microorganisms in Intertriginous Psoriasis: No Evidence of Candida
INGELA FLYTSTRÖM A2, ING-MARIE BERGBRANT A2, JOHANNA BRÅRED A2, LENA LIND BRANDBERG A3
Infection can be a trigger and an aggravating factor in psoriasis. Antibacterial and/or antifungal agents are commonly used in the treatment of intertriginous psoriasis, because it is believed that flexures in psoriasis are often colonized by Candida species and Staphylococcus aureus. Bacterial and fungal cultures were studied from 32 psoriatic patients with no topical treatment in t ...
Pages: 121-123
Abstract  PDF
LETTER TO THE EDITOR
Detection of Herpes Virus Genomes in Skin Lesions from Patients with Behçet's Disease and Other Related Inflammatory Diseases
MICHIKO TOJO A1, XUEYI ZHENG A1, HIROKATSU YANAGIHORI A1, NORITAKA OYAMA A1, KAZUO TAKAHASHI A2, KOICHIRO NAKAMURA A1, FUMIO KANEKO A1
Although the aetiology of Behçet's disease is still poorly understood, viral infection has long been postulated as one of the factors. To investigate the relationship between herpes viruses and Behçet's disease, we used polymerase chain reaction to detect herpes simplex virus 1 (HSV-1) and 2 (HSV-2), and human herpes virus 6 (HHV-6) and 7 (HHV-7) DNA in samples of lesional tissues from patients ...
Pages: 124-127
Abstract  PDF
LETTER TO THE EDITOR
Human Herpes Virus 6 Encephalitis in Allopurinol-induced Hypersensitivity Syndrome
TARO MASAKI A1, ATSUSHI FUKUNAGA A1, MIKIKO TOHYAMA A2, YOSHIYUKI KODA A3, SHIHO OKUDA A3, NOBUYA MAEDA A3, FUMIO KANDA A3, MASAKI YASUKAWA A4, KOJI HASHIMOTO A2, TATSUYA HORIKAWA A1, MASATO UEDA A1
Hypersensitivity syndrome is one of the most severe forms of drug eruption, and is characterized by a severe, potentially lethal, multiorgan involvement. Recently, reactivation of human herpesvirus 6 (HHV-6) has been suggested to be involved in this syndrome, although the exact role of HHV-6 remains elusive. In addition to exanthem subitum, neurological illnesses, such as infantile febrile illness ...
Pages: 128-131
Abstract  PDF
Lupus Vulgaris in a Skin Graft
Michael Bock A2, Oliver Nolte A3, Wolfgang Hartschuh A2, Uta Jappe A2
This article does not have an abstract.
Pages: 132-133
Abstract  PDF
Erythema Gyratum Repens Accompanied by Essential Thrombocythemia, Followed by a Blastic Crisis
Takahiro Kiyohara A1, Masanobu Kumakiri A1, Hitoshi Kobayashi A2, Mariko Mayuzumi A2, Akira Ohkawara A2
This article does not have an abstract.
Pages: 133-134
Abstract  PDF
A de Novo Mutation in the Keratin 9 Gene in a Family with Epidermolytic Palmoplantar Keratoderma from Northern Sweden
Elke Weisshaar1,2, Michael J. Kucenic1 and Alan B. Fleischer Jr1.
This article does not have an abstract.
Pages: 135-137
Abstract  PDF
A Novel Insertion Mutation in COL7A1 Identified in Hallopeau-Siemens Recessive Dystrophic Epidermolysis Bullosa
Kazuko C. Sato-Matsumura A1, Daisuke Sawamura A1, Mikio Goto A2, Maki Goto A1, Hideki Nakamura A1, Hiroshi Shimizu A1
This article does not have an abstract.
Pages: 137-138
Abstract  PDF
A Case of Adult T-cell Leukemia/Lymphoma with an Indolent Clinical Course has an Unusual Proviral DNA Integration Pattern
Takehiko Tsuda A1, Masashi Ishikawa A1, Tomohiro Banno A1, Hiroshi Fujisawa A1, Sumihisa Imakado A1, Fujio Otsuka A1
This article does not have an abstract.
Pages: 139-140
Abstract  PDF
Severe Mucocutaneous Necrotizing Vasculitis Associated with the Combination of Chloroquine and Proguanil
Minh Son Luong A2, Didier Bessis A2, Nadia Raison-Peyron A2, Véronique Pinzani A3, Jean-Jacques Guilhou A2, Bernard Guillot A2
This article does not have an abstract.
Page: 141
Abstract  PDF
Lumbosacral Hypertrichosis Treated with the Normal-mode Ruby Laser
Rajini Mahendran A1 and Robert A. Sheehan-Dare A1
This article does not have an abstract.
Pages: 142-143
Abstract  PDF
Superinfection of Eczema with Multiple Acinetobacter Species
Noah Scheinfeld A1
This article does not have an abstract.
Page: 143
Abstract  PDF
Isolated Plantar Collagenoma
This article does not have an abstract.
Page: 144
Abstract  PDF
Severe Generalized Ulcerative Lichen Planus
Darrell Rigel; Brian Berman
This article does not have an abstract.
Pages: 145-146
Abstract  PDF
LETTER TO THE EDITOR
Long-term Involution of Unilateral Porokeratotic Eccrine Ostial and Dermal Duct Naevus
José Mazuecos A2, Miguel Ortega A2, Juan José Ríos A3, Francisco Camacho A2
This article does not have an abstract.
Pages: 147-149
Abstract  PDF
LETTER TO THE EDITOR
Venous Leg Ulcers in a Patient with Klinefelter's Syndrome and Increased Activity of Plasminogen Activator Inhibitor-1
Joachim Dissemond A1, Thomas Schultewolter A1, Tilmann C. Brauns A1, Manfred Goos A1, Stephan N. Wagner A1
This article does not have an abstract.
Pages: 149-150
Abstract  PDF
Ulcerated Necrobiosis Lipoidica Treated with Cyclosporin A
Giuseppe Stinco A1, Maria Elena Parlangeli A1, Vincenzo De Francesco A1, Alfonsina Frattasio A1, Maurizio Germino A1, Pasquale Patrone A1
This article does not have an abstract.
Pages: 151-153
Abstract  PDF
LETTER TO THE EDITOR
Pyoderma Gangrenosum Associated with Sarcoidosis
G. Kontochristopoulos A1, E. Saxioni A1, G. Doulaveri-Gherasim A1, G. Politis A2, N. Zakopoulou A1
Pages: 153-154
Abstract  PDF
LETTER TO THE EDITOR
Divided Naevus of the Penis: A Hypothesis on the Embryological Mechanism of its Development
Taro Kono A2, Motohiro Nozaki A2, Yuji Kikuchi A2, Ali Riza Erçöçen A4, Nobukazu Hayashi A3, Henry H. L. Chan A5, Rei Ohkubo A2, Eri Fukaya A2
This article does not have an abstract.
Pages: 155-156
Abstract  PDF
Adult Multiple Xanthogranulomas with Spontaneous Resolution
Sung-Jan Lin A1 and Hsien-Ching Chiu* A1
This article does not have an abstract.
Pages: 157-158
Abstract  PDF