Content - Volume 83, Issue 2
All articles
This article does not have an abstract.
Page: 81
Torbjörn Egelrud
This article does not have an abstract.
Pages: 81-82
LETTER TO THE EDITOR
Prolonged stability and controlled expression of gene constructs transferred directly to human skin improve the possibility of using this tissue in somatic gene therapy. We aim to develop a simple transfection method resulting in retroviral mediated gene transfer to keratinocyte stem cells in situ. We here show that after DNA-mediated gene transfer into primary human keratinocytes it is pos ...
Pages: 83-87
LETTER TO THE EDITOR
Many women use panty liners between menstrual periods. The aim of this study was to investigate whether the use of such products might influence the vulva skin. Twelve healthy women were studied on four occasions with three different product constructions and on one occasion without products. Temperature, surface wetness and surface pH were measured on vulva skin. Mean skin temperature when the wo ...
Pages: 88-92
LETTER TO THE EDITOR
The aim of this study was to evaluate whether a moisturizer used on normal skin can increase skin response to allergens. Twelve nickel-allergic volunteers applied a lipid-rich moisturizer on the upper arm 3 times daily for 7 days, while the other upper arm served as a control. A control group followed the same treatment protocol. Following treatment with moisturizer, patch tests with 1% NiCl
Pages: 93-97
LETTER TO THE EDITOR
The checkpoint protein p53, which is activated by DNA damage, is involved in the decision whether the cells should stop replication and proceed to repair their DNA or die by apoptosis. We evaluate the expression of p53 and the number of apoptotic cells in normal sun-exposed (face) and protected (abdomen) skin in Egyptians between 6 and 77 years of age. The degree of p53 expression in facial skin s ...
Pages: 98-104
LETTER TO THE EDITOR
To investigate the pathophysiological role of fibroblasts in tissue metabolism, we analysed gelatin-degrading enzymes secreted from skin
cells in culture. Using a gelatin-zymography method, matrix metalloproteinase (MMP)-2 was constitutively secreted from fibroblasts,
whereas both MMP-2 and MMP-9 were secreted from keratinocytes. MMP-9
expression by fibroblasts was induced by the addition of tr ...
Pages: 105-107
LETTER TO THE EDITOR
Keratinocyte hyperproliferation, inflammatory infiltrates, neoangiogenesis and alterations in cytokine levels are hallmarks of psoriatic skin. Matrix metalloproteinases (MMPs) have been associated with the remodeling of the extracellular matrix during inflammation, neovascularization, and malignant transformation. We have previously shown that particularly MMP-12 is abundantly expressed by macroph ...
Pages: 108-114
LETTER TO THE EDITOR
The manifestation of porphyria cutanea tarda reflects genetic and environmental factors. Mutations in the uroporphyrinogen decarboxylase gene, located at chromosome 1p34, discriminate familial porphyria cutanea tarda from sporadic cases. Furthermore, mutations in the haemochromatosis gene may be involved in the aetiology. In this study 53 unrelated Danish patients with porphyria cutanea tarda were ...
Pages: 115-120
LETTER TO THE EDITOR
Infection can be a trigger and an aggravating factor in psoriasis. Antibacterial and/or antifungal agents are commonly used in the treatment of intertriginous psoriasis, because it is believed that flexures in psoriasis are often colonized by Candida species and Staphylococcus aureus. Bacterial and fungal cultures were studied from 32 psoriatic patients with no topical treatment in t ...
Pages: 121-123
LETTER TO THE EDITOR
Although the aetiology of Behçet's disease is still poorly understood, viral infection has long been postulated as one of the factors. To investigate the relationship between herpes viruses and Behçet's disease, we used polymerase chain reaction to detect herpes simplex virus 1 (HSV-1) and 2 (HSV-2), and human herpes virus 6 (HHV-6) and 7 (HHV-7) DNA in samples of lesional tissues from patients ...
Pages: 124-127
LETTER TO THE EDITOR
Hypersensitivity syndrome is one of the most severe forms of drug eruption, and is characterized by a severe, potentially lethal, multiorgan involvement. Recently, reactivation of human herpesvirus 6 (HHV-6) has been suggested to be involved in this syndrome, although the exact role of HHV-6 remains elusive. In addition to exanthem subitum, neurological illnesses, such as infantile febrile illness ...
Pages: 128-131
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Pages: 132-133
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Pages: 133-134
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Pages: 135-137
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Pages: 137-138
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Pages: 139-140
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Page: 141
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Pages: 142-143
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Page: 143
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Page: 144
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Pages: 145-146
LETTER TO THE EDITOR
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Pages: 147-149
LETTER TO THE EDITOR
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Pages: 149-150
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Pages: 151-153
LETTER TO THE EDITOR
Pages: 153-154
LETTER TO THE EDITOR
This article does not have an abstract.
Pages: 155-156
Sung-Jan Lin A1 and Hsien-Ching Chiu* A1
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Pages: 157-158
Anders Vahlquist
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Page: 159
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Page: 159
