Content

Content - Volume 83, Issue 2

Editor's choice in this issue

All articles

Porphyria Cutanea Tarda Still much to be learnt
This article does not have an abstract.
Page: 81
Abstract  PDF
MMPs: They are there and they do something - also in Dermatology
Torbjörn Egelrud
This article does not have an abstract.
Pages: 81-82
Abstract  PDF
LETTER TO THE EDITOR
Production of Retroviral Vectors in Primary Human Keratinocytes after DNA-Mediated Gene Transfer Leads to Prolonged Gene Expression
Prolonged stability and controlled expression of gene constructs transferred directly to human skin improve the possibility of using this tissue in somatic gene therapy. We aim to develop a simple transfection method resulting in retroviral mediated gene transfer to keratinocyte stem cells in situ. We here show that after DNA-mediated gene transfer into primary human keratinocytes it is pos ...
Pages: 83-87
Abstract  PDF
LETTER TO THE EDITOR
The Vulva Skin Microclimate: Influence of Panty Liners on Temperature, Humidity and pH
Many women use panty liners between menstrual periods. The aim of this study was to investigate whether the use of such products might influence the vulva skin. Twelve healthy women were studied on four occasions with three different product constructions and on one occasion without products. Temperature, surface wetness and surface pH were measured on vulva skin. Mean skin temperature when the wo ...
Pages: 88-92
Abstract  PDF
LETTER TO THE EDITOR
Effect of a Moisturizer on Skin Susceptibility to NiCl2
The aim of this study was to evaluate whether a moisturizer used on normal skin can increase skin response to allergens. Twelve nickel-allergic volunteers applied a lipid-rich moisturizer on the upper arm 3 times daily for 7 days, while the other upper arm served as a control. A control group followed the same treatment protocol. Following treatment with moisturizer, patch tests with 1% NiCl
Pages: 93-97
LETTER TO THE EDITOR
Expression of p53 in Normal Sun-exposed and Protected Skin (Type IV-V) in Different Decades of Age
The checkpoint protein p53, which is activated by DNA damage, is involved in the decision whether the cells should stop replication and proceed to repair their DNA or die by apoptosis. We evaluate the expression of p53 and the number of apoptotic cells in normal sun-exposed (face) and protected (abdomen) skin in Egyptians between 6 and 77 years of age. The degree of p53 expression in facial skin s ...
Pages: 98-104
Abstract  PDF
LETTER TO THE EDITOR
Matrix Metalloproteinases-2 and -9 are Secreted from Human Fibroblasts
To investigate the pathophysiological role of fibroblasts in tissue metabolism, we analysed gelatin-degrading enzymes secreted from skin cells in culture. Using a gelatin-zymography method, matrix metalloproteinase (MMP)-2 was constitutively secreted from fibroblasts, whereas both MMP-2 and MMP-9 were secreted from keratinocytes. MMP-9 expression by fibroblasts was induced by the addition of tr ...
Pages: 105-107
Abstract  PDF
LETTER TO THE EDITOR
Matrix Metalloproteinase-19 is Expressed by Keratinocytes in Psoriasis
Keratinocyte hyperproliferation, inflammatory infiltrates, neoangiogenesis and alterations in cytokine levels are hallmarks of psoriatic skin. Matrix metalloproteinases (MMPs) have been associated with the remodeling of the extracellular matrix during inflammation, neovascularization, and malignant transformation. We have previously shown that particularly MMP-12 is abundantly expressed by macroph ...
Pages: 108-114
Abstract  PDF
LETTER TO THE EDITOR
Familial and Sporadic Porphyria Cutanea Tarda: Clinical, Biochemical and Genetic Features with Emphasis on Iron Status
The manifestation of porphyria cutanea tarda reflects genetic and environmental factors. Mutations in the uroporphyrinogen decarboxylase gene, located at chromosome 1p34, discriminate familial porphyria cutanea tarda from sporadic cases. Furthermore, mutations in the haemochromatosis gene may be involved in the aetiology. In this study 53 unrelated Danish patients with porphyria cutanea tarda were ...
Pages: 115-120
Abstract  PDF
LETTER TO THE EDITOR
Microorganisms in Intertriginous Psoriasis: No Evidence of Candida
Infection can be a trigger and an aggravating factor in psoriasis. Antibacterial and/or antifungal agents are commonly used in the treatment of intertriginous psoriasis, because it is believed that flexures in psoriasis are often colonized by Candida species and Staphylococcus aureus. Bacterial and fungal cultures were studied from 32 psoriatic patients with no topical treatment in t ...
Pages: 121-123
Abstract  PDF
LETTER TO THE EDITOR
Detection of Herpes Virus Genomes in Skin Lesions from Patients with Behçet's Disease and Other Related Inflammatory Diseases
Although the aetiology of Behçet's disease is still poorly understood, viral infection has long been postulated as one of the factors. To investigate the relationship between herpes viruses and Behçet's disease, we used polymerase chain reaction to detect herpes simplex virus 1 (HSV-1) and 2 (HSV-2), and human herpes virus 6 (HHV-6) and 7 (HHV-7) DNA in samples of lesional tissues from patients ...
Pages: 124-127
Abstract  PDF
LETTER TO THE EDITOR
Human Herpes Virus 6 Encephalitis in Allopurinol-induced Hypersensitivity Syndrome
Hypersensitivity syndrome is one of the most severe forms of drug eruption, and is characterized by a severe, potentially lethal, multiorgan involvement. Recently, reactivation of human herpesvirus 6 (HHV-6) has been suggested to be involved in this syndrome, although the exact role of HHV-6 remains elusive. In addition to exanthem subitum, neurological illnesses, such as infantile febrile illness ...
Pages: 128-131
Abstract  PDF
Lupus Vulgaris in a Skin Graft
This article does not have an abstract.
Pages: 132-133
Abstract  PDF
Lumbosacral Hypertrichosis Treated with the Normal-mode Ruby Laser
This article does not have an abstract.
Pages: 142-143
Abstract  PDF
Superinfection of Eczema with Multiple Acinetobacter Species
This article does not have an abstract.
Page: 143
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Isolated Plantar Collagenoma
This article does not have an abstract.
Page: 144
Abstract  PDF
Severe Generalized Ulcerative Lichen Planus
This article does not have an abstract.
Pages: 145-146
Abstract  PDF
LETTER TO THE EDITOR
Long-term Involution of Unilateral Porokeratotic Eccrine Ostial and Dermal Duct Naevus
This article does not have an abstract.
Pages: 147-149
Abstract  PDF
Ulcerated Necrobiosis Lipoidica Treated with Cyclosporin A
This article does not have an abstract.
Pages: 151-153
Abstract  PDF
LETTER TO THE EDITOR
Divided Naevus of the Penis: A Hypothesis on the Embryological Mechanism of its Development
This article does not have an abstract.
Pages: 155-156
Abstract  PDF
Adult Multiple Xanthogranulomas with Spontaneous Resolution
Sung-Jan Lin A1 and Hsien-Ching Chiu* A1
This article does not have an abstract.
Pages: 157-158
Abstract  PDF