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Content - Volume 86, Issue 1

Editor's choice in this issue

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IN THIS ISSUE
Promising results with topical tacrolimus in plaque psoriasis
Torbjörn Egelrud
Section Editor
Page: 1
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IN THIS ISSUE
Topical calcineurin inhibitors and ultraviolet light therapy – a “no-go-zone”?
Kristian Thestrup-Pedersen
Section Editor
Pages: 1-2
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IN THIS ISSUE
Editorial News – 2006
Anders Vahlquist, Editor-in-Chief
Agneta Andersson, Editorial Manager
Page: 2
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INVESTIGATIVE REPORT
Phenotypic Variation and Allelic Heterogeneity in Young Patients with Papillon-Lefèvre Syndrome
Christer ULLBRO 1,4, Safia EL-SAMADI 2, Christine BOUMAH 2, Nujoud AL-YOUSEF 2, Salma WAKIL 2, Svante TWETMAN 4, Abdullah ALFADLEY 3, Kristian THESTRUP-PEDERSEN 3 and Brian MEYER 2
Papillon-Lefèvre syndrome is an autosomal recessive disorder characterized by palmoplantar hyperkeratosis and aggressive periodontitis. The aim of the study was to identify underlying cathepsin C mutations in 39 subjects with Papillon-Lefèvre syndrome and to explore any phenotypic associations. Genotyping and mutation analyses were performed using standard molecular techniques, and dermatologic ...
Pages: 3-7
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INVESTIGATIVE REPORT
Increased Retest Reactivity by Both Patch and Use Test with Methyldibromoglutaronitrile in Sensitized Individuals
Charlotte D. JENSEN 1,2, Jeanne Duus JOHANSEN 2, Torkil MENNé 2,3 and Klaus Ejner ANDERSEN 1,2
Hyperreactivity on re-exposure of previous allergic contact dermatitis skin areas has been previously demonstrated. This study aimed to investigate in methyldibromoglutaronitrile (MDBGN) allergic patients whether skin with previous allergic dermatitis from MDBGN showed an augmented response on re-exposure by both a patch test challenge and a use test with a liquid soap preserved with MDBGN. MDBGN ...
Pages: 8-12
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INVESTIGATIVE REPORT
Prolonged Topical Application of Tacrolimus Inhibits Immediate Hypersensitivity Reactions by Reducing Degranulation of Mast Cells
Tomoko INOUE, Norito KATOH and Saburo KISHIMOTO
We studied the effects of prolonged topical application of tacrolimus on immediate hypersensitivity reactions. Tacrolimus, betamethasone or petrolatum was applied to the footpad of mice for up to 28 days after immunization, and the foot-swelling response to allergen was estimated. The reactions in tacrolimus-treated mice decreased significantly from day 14, while those in betamethasone-treated mi ...
Pages: 13-16
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INVESTIGATIVE REPORT
Effect of Psoriasis Activity on Metalloproteinase-1 and Tissue Inhibitor of Metalloproteinase-1 in Plasma and Lesional Scales
Iwona FLISIAK, Piotr POREBSKI and Bozena CHODYNICKA
The aim of this study was to evaluate the association between psoriasis severity and concentrations of matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in plasma and scales from psoriatic lesions, measured with an enzyme immunoassay in 24 patients and analysed with respect to psoriasis area and severity index (PASI). The mean plasma concentrations of both pr ...
Pages: 17-21
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CLINICAL REPORT
Treatment of Palmoplantar Psoriasis with Monochromatic Excimer Light (308-nm) Versus Cream PUVA
Norbert J. NEUMANN, Natalia MAHNKE, Dorothea KORPUSIK, Helger STEGE and Thomas RUZICKA
Palmoplantar psoriasis is a chronic disease, which is very resistant to treatment and often leads to severe disabilities. Photochemotherapy employing psoralens combined with UVA irradiation (PUVA) is a well-accepted therapy for palmoplantar psoriasis. Its topical application (bath PUVA; cream PUVA) avoids the typical side effects of orally applied psoralens. We compared the efficacy of cream PUVA ...
Pages: 22-24
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CLINICAL REPORT
Topical Photodynamic Therapy for Prevention of New Skin Lesions in Renal Transplant Recipients
Hans Christian WULF 1, Stan PAVEL 2, Ida STENDER 1 and Christianne AHB BAKKER-WENSVEEN 2
Preclinical data suggest that topical methyl aminolevulinate photodynamic therapy may have potential in preventing new skin lesions in transplant recipients. An open intra-patient randomized study investigated the prevention potential of this treatment in 27 renal transplant patients with actinic keratoses and other skin lesions in two circular contralateral areas (5 cm diameter). The treatment a ...
Pages: 25-28
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CLINICAL REPORT
0.3% Tacrolimus Gel and 0.5% Tacrolimus Cream Show Efficacy in Mild to Moderate Plaque Psoriasis: Results of a Randomized, Open-label, Observer-blinded Study
Jean-Paul ORTONNE 1, Peter C. M. van de KERKHOF 2, Jörg C. PRINZ 3, Thomas BIEBER 4, Morad LAHFA 5, Andris RUBINS 6, Gottfried WOZEL 7 and Gérard LORETTE 8 on behalf of the European Tacrolimus Psoriasis Study Group
The efficacy and safety of 0.3% tacrolimus gel and 0.5% tacrolimus cream compared with calcipotriol ointment were evaluated in adults ( n =124) with mild to moderate plaque psoriasis. Treatment was twice daily for a maximum of 12 weeks. Clinical efficacy was assessed by the percentage change in the local psoriasis severity index of a target lesion between baseline and week 12. By week 12 ...
Pages: 29-33
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CLINICAL REPORT
Pimecrolimus and Narrowband UVB as Monotherapy or Combination Therapy in Children and Adolescents with Atopic Dermatitis
Tien-Yi TZUNG 1, Chyi-Bin LIN 1, Ya-Hui CHEN 1 and Chia-Yi YANG 2
Topical pimecrolimus and narrowband ultraviolet B (UVB) are both known to be effective in treating atopic dermatitis. We compared the clinical efficacy of monotherapy with either twice daily topical 1% pimecrolimus cream or twice weekly narrowband UVB, and combination therapy in 26 children and adolescents with moderate to severe atopic dermatitis in a half-side manner for 6 weeks. Twenty-four pa ...
Pages: 34-38
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CLINICAL REPORT
Clinical Spectrum of Cutaneous Langerhans’ Cell Histiocytosis Mimicking Various Diseases
Kerstin QUERINGS, Hans STARZ and Bernd-Rüdiger BALDA
Langerhans’ cell histiocytosis summarizes a spectrum of diseases on the basis of histogenetic criteria. These are characterized by an accumulation of cells with Langerhans’ cell phenotype in one or multiple organs. Up to 50% of patients with either single or multi-organ manifestation of Langerhans’ cell histiocytosis initially present with cutaneous symptoms. Nevertheless, cutaneous Langerha ...
Pages: 39-43
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CLINICAL REPORT
Metastasis of a Malignant Melanoma 2 Years after Carbon Dioxide Laser Treatment of a Pigmented Lesion: Case Report and Review of the Literature
Christina GOTTSCHALLER, Ulrich HOHENLEUTNER and Michael LANDTHALER
A 64-year-old woman with a clinically diagnosed ‘lentigo simplex’ on her right cheek was dermatologically treated several times with a CO 2 laser. Three years later she showed a metastasis of a malignant melanoma in her right parotid gland. Considering this case, as well as other published cases reporting malignant melanomas occurring after laser treatment, we again underscore that ...
Pages: 44-47
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CLINICAL REPORT
Clinicopathological Analysis of 1571 Cutaneous Malignant Melanomas in Valencia, Spain: Factors Related to Tumour Thickness
Eduardo NAGORE 1, Vicente OLIVER 2, Rafael BOTELLA-ESTRADA 1, Salvador MORENO-PICOT 3, Carlos GUILLéN 1 and José M. FORTEA 2
Epidemiological studies on cutaneous melanoma in Mediterranean countries are scarce. Our aim was to perform a descriptive analysis of melanoma cases diagnosed in Valencia, Spain, and to evaluate the relationship between Breslow thickness and some clinical features. A total of 1571 patients with histologically confirmed cutaneous malignant melanoma diagnosed at the two main referral melanoma centre ...
Pages: 50-56
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LETTER TO THE EDITOR
Dovobet ® Ointment Under Occlusion Overnight for Troublesome Scalp Psoriasis
Anthony M.R. Downs
This article does not have an abstract.
Pages: 57-58
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LETTER TO THE EDITOR
Darier’s Disease Associated with Cutis Verticis Gyrata, Hyperprolactinaemia and Depressive Disorder
Emoke Rácz 1, Zoltán Kornseé 1, Márta Csikós 1, Matild Dobos 2, Pál Salacz 3 and Sarolta Kárpáti 1
This article does not have an abstract.
Pages: 59-60
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LETTER TO THE EDITOR
Cyclin A Expression in Chronic Leg Ulcers
Katarina Lundqvist and Artur Schmidtchen
This article does not have an abstract.
Pages: 61-62
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LETTER TO THE EDITOR
Tumoral Macroglobulinosis of the Skin: In Situ Release of IgM
Jean-Marie Bonnetblanc, Christophe Bedane, Jacqueline Fayol and François Labrousse
This article does not have an abstract.
Pages: 63-64
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LETTER TO THE EDITOR
Systemic Absorption of Topical Tacrolimus in Pyoderma Gangrenosum
Gerard Pitarch, Arantxa Torrijos, Laura Mahiques, José Luís Sánchez-Carazo and José Miguel Fortea
This article does not have an abstract.
Pages: 64-65
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LETTER TO THE EDITOR
An Incomplete Circle of Alopecia: A New Case of Halo Scalp Ring?
Annalisa Patrizi, Francesco Savoia, Iria Neri and Federico Bardazzi
This article does not have an abstract.
Pages: 65-66
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LETTER TO THE EDITOR
Churg-Strauss Syndrome with Cutaneous and Neurological Manifestations Preceding Asthma
Tamihiro Kawakami, Yoshinao Soma, Eri Hosaka and Masako Mizoguchi
This article does not have an abstract.
Pages: 67-68
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LETTER TO THE EDITOR
Pimecrolimus Cream 1% is Effective in Seborrhoeic Dermatitis Refractory to Treatment with Topical Corticosteroids
Paulo Rowilson Cunha
This article does not have an abstract.
Pages: 69-70
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LETTER TO THE EDITOR
Pimecrolimus Cream 1% is Effective in a Case of Granulomatous Rosacea
Paulo Rowilson Cunha1 and Ana Beatris Rossi2
This article does not have an abstract.
Pages: 71-72
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LETTER TO THE EDITOR
Postherpetic Paresis Mimicking an Abdominal Herniation
Andrea Giuliani 1, Gaspare Galati 1, Leoluca Parisi 2, Teresa Ricciardulli 1, Michelangelo Bartolo 2, Elvira Tartaglia 1, Miriam Grimaldi 3 and Guglielmo Pranteda 2 *
This article does not have an abstract.
Pages: 73-74
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LETTER TO THE EDITOR
Bullous Lesions in Chronic Lymphocytic Leukaemia: Pemphigoid or Insect Bites?
Ugo Bottoni 1, Francesca Romana Mauro 2, Emanuele Cozzani 3, Daniele Innocenzi 1, Maura Del Giudice 1, Aurora Parodi 3, Alfredo Rebora 3, Franco Mandelli 2 and Stefano Calvieri 1
This article does not have an abstract.
Pages: 74-76
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LETTER TO THE EDITOR
Point Mutation in the STS Gene in a Severely Affected Patient with X-linked Recessive Ichthyosis
Luz M. Gonzalez-Huerta 1, Olga M. Messina-Baas 2, Jaime Toral-Lopez 1, María R. Rivera-Vega, Susana Kofman-Alfaro 1 and Sergio A. Cuevas-Covarrubias 1 *
This article does not have an abstract.
Pages: 78-79
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LETTER TO THE EDITOR
Neurofibromatosis 1/Noonan Syndrome Associated with Hashimoto’s Thyroiditis and Vitiligo
Başak Yalcçın, Emine Tamer, Güneş Gür, Pınar Öztas, Muhterem Üstün Polat and Nuran Allı
This article does not have an abstract.
Pages: 80-81
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LETTER TO THE EDITOR
Digital Arteriovenous Malformation
Sun Young Yoon, Sang Hyun Cho and Jeong Deuk Lee
This article does not have an abstract.
Pages: 82-83
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LETTER TO THE EDITOR
Successful Treatment of Pyoderma Gangrenosum with Potassium Iodide
Akihiko Asahina, Yohei Minatani, Yayoi Tada, Hiroshi Mitsui and Kunihiko Tamaki
This article does not have an abstract.
Pages: 84-85
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LETTER TO THE EDITOR
Giant Dermatofibroma Appearing During Pregnancy
Tamara Micantonio, Maria Concetta Fargnoli and Ketty Peris
This article does not have an abstract.
Pages: 86-87
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LETTER TO THE EDITOR
Long-lasting Remission of Pemphigus Vulgaris Treated with Rituximab
Maria Esposito, Elisabetta Capriotti, Alessandro Giunta, Luca Bianchi and Sergio Chimenti*
This article does not have an abstract.
Pages: 87-89
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LETTER TO THE EDITOR
Strawberry Gingivitis: An Isolated Manifestation of Wegener’s Granulomatosis?
Silvia Vanessa Lourenço 1,2 and Marcello Menta Simonsen Nico 1
This article does not have an abstract.
Pages: 90-91
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LETTER TO THE EDITOR
Naevus Lipomatosus Cutaneous Superficialis of Hoffmann-Zurhelle with Angiokeratoma of Fordyce
Nawaf Al-Mutairi, Arun Joshi and Osama Nour-Eldin
This article does not have an abstract.
Pages: 92-93
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BOOK REVIEW
Book review

Hans Törmä

Department of Medical Sciences/Dermatology

University Hospital

SE-751 85 Uppsala

Sweden

This article does not have an abstract.
Pages: 94-0
Abstract  PDF
BOOK REVIEW
Book review

Kristian Thestrup-Pedersen

Section Editor

This article does not have an abstract.
Pages: 94-0
Abstract  PDF
ANNOUNCEMENT
Announcement
Pages: 95-0
Abstract  PDF