Content

Content - Volume 91, Issue 5

Editors choice in this issue

REVIEW
Are All Melanomas Dangerous?
Carsten Nørgaard, Martin Glud, Robert Gniadecki
The increased incidence of cutaneous malignant melanoma, together with only minor changes in mortality, has brought into question the existence of a melanoma epidemic. The discrepancy between incidence and mortality suggests that most newly diagnosed melanomas have indolent behaviour. This review summarizes the most recent epidemiological findings regarding the incidence of cutaneous malignant mel ...
Pages: 499-503
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CLINICAL REPORT
Clinical Analysis of Skin Lesions in 796 Chinese HIV- positive Patients
Xiao-jie Huang, Hai-ying Li, De-xi Chen, Xi-cheng Wang, Zai-chun Li, Ya-song Wu, Tong Zhang, Yan-qing Gao, Hao Wu
Skin lesions are often associated with human immunodeficiency virus (HIV) infection, reflecting the immunocompromised status of the individual. We investigated the relationship between skin lesions and immune function in a retrospective study of 796 Chinese HIV patients with and without highly active antiretroviral therapy (HAART). Of the 651 patients who had not received HAART, we found that 531 ...
Pages: 552-556
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LETTER TO THE EDITOR
Recurrent Subacute Cutaneous Lupus Erythematosus Following Exposure to Different Drugs
Aikaterini I. Liakou, Martina Brunner , Michael J. Theodorakis, Evgenia Makrantonaki, Christos C. Zouboulis
Abstract is missing (Letter)
Pages: 586-587
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All articles

REVIEW
Are All Melanomas Dangerous?
Carsten Nørgaard, Martin Glud, Robert Gniadecki
The increased incidence of cutaneous malignant melanoma, together with only minor changes in mortality, has brought into question the existence of a melanoma epidemic. The discrepancy between incidence and mortality suggests that most newly diagnosed melanomas have indolent behaviour. This review summarizes the most recent epidemiological findings regarding the incidence of cutaneous malignant mel ...
Pages: 499-503
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INVESTIGATIVE REPORT
Validation of a Model of Itch Induction for Brain Positron Emission Tomography Studies Using Histamine Iontophoresis
Laure Bergeret, David Black, Jennifer Theunis, Laurent Misery, Nicolas Chauveau, Florent Aubry, Hélène Gros, Gérard Viallard, Pierre Celsis
Skin-brain signalling in itch reactions has been demonstrated with neuroimaging techniques showing specific brain activation. With positron emission tomography (PET), the itch model used must be adapted to technical and practical constraints. The technique of itch induction by histamine iontophoresis enables modulation of the sensation via the electrical charge applied. This itch model was validat ...
Pages: 504-510
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INVESTIGATIVE REPORT
Stability of the Cathelicidin Peptide LL-37 in a Non-healing Wound Environment
Alvar Grönberg, Louise Zettergren , Magnus S. Ågren
The endogenous cathelicidin peptide LL-37 is strongly expressed at the wound edge early in the process of acute wound healing, but only weakly expressed in chronic wounds. Excessive proteolysis may limit the therapeutic usefulness of exogenous LL-37, especially in ulcers colonized with Pseudomonas aeruginosa that produce elastase, which degrades LL-37. This study investigated the stability of synt ...
Pages: 511-515
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INVESTIGATIVE REPORT
Normal Endothelial Function in Patients with Mild-to-Moderate Psoriasis: A Case-control Study
Peter Jensen, Claus Zachariae, Peter Hansen, Lone Skov
Evidence is increasing that severe psoriasis is an independent cardiovascular risk factor. Results from case-control studies of endothelial dysfunction, a marker of early atherosclerosis, in patients with moderate-to-severe psoriasis have been conflicting and were conducted with operator-dependent and technically demanding ultrasound measurement of brachial artery flow-mediated vasodilation. There ...
Pages: 516-520
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INVESTIGATIVE REPORT
Survival Data for 299 Patients with Primary Cutaneous Lymphomas: A Monocentre Study
Christian Hallermann, Christoph Niermann, Rudolf-Josef Fischer, Hans-Joachim Schulze
The aim of this study was retrospectively to assess the validity of the 2005 WHO-EORTC classification for primary cutaneous lymphomas (PCL) in a large cohort of patients of a single German skin cancer unit. All patients with PCLs consecutively visiting our hospital between January 1980 and December 2005 were included in a retrospective monocentre study, analysing their histological and clinical da ...
Pages: 521-525
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INVESTIGATIVE REPORT
Validation of Self-testing as a Method to Estimate the Prevalence of Nickel Allergy
Anna Josefson, Åke Svensson, Gunilla Färm, Malin Engfeldt, Birgitta Meding
The aim of this study was to investigate the validity of self-patch testing for nickel allergy, in order to determine a cost-effective method for surveillance of the prevalence of nickel allergy. Population-based study including patch testing is the most reliable method to study the prevalence of allergy, but it is expensive and has logistical problems. A total of 191 dermatology patients referred ...
Pages: 526-530
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INVESTIGATIVE REPORT
Acne as Seen by Adolescents: Results of Questionnaire Study in 852 French Individuals
Florence Poli, Nicole Auffret, Claire Beylot, Martine Chivot, Michel Faure, Dominique Moyse , Henri Pawin, Jean Revuz, Brigitte Dréno
Acne can have an important psychological impact. We surveyed 852 adolescents aged 12–25 years about their knowledge of acne and its treatment in a non-medical context. The study involved a questionnaire administered to callers to a youth telephone helpline in France. Callers were categorized into those who currently had acne, those who had had acne previously, and those who had never had acne. M ...
Pages: 531-536
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INVESTIGATIVE REPORT
Differences in Itch Characteristics Between Psoriasis and Atopic Dermatitis Patients: Results of a Web-based Questionnaire
Jenna L. O'Neill, Yiong-Huak Chan, Stephen R. Rapp, Gil Yosipovitch
Differences in itch characteristics between different inflammatory dermatoses are not well described. The aim of this study was to assess differences in itch characteristics between patients with psoriasis and atopic dermatitis using a previously validated web-based questionnaire that was made available through the National Psoriasis Foundation and National Eczema Association for Science and Educa ...
Pages: 537-540
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INVESTIGATIVE REPORT
Insulin Resistance is Increased in Patients with Vitiligo
Ayse Serap Karadag, Emre Tutal, Derun Taner Ertugrul
The aim of this study was to evaluate the relationship between vitiligo and insulin resistance (IR). A total of 96 subjects were included in the study; 57 patients with vitiligo and 39 subjects in an age and a body mass index-matched control group. In fasting blood samples, insulin, C-peptide, glucose, total cholesterol, triglyceride, low-density lipoprotein-cholesterol (LDL-C) and high-density li ...
Pages: 541-544
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CLINICAL REPORT
Predictors of Pain Associated with Photodynamic Therapy: A Retrospective Study of 658 Treatments
Christina B. Halldin, Martin Gillstedt, John Paoli, Ann-Marie Wennberg, Helena Gonzalez
Pain is the most common side-effect of photodynamic therapy (PDT). Our main objective was to identify pain predictors in PDT. In total, we performed 658 treatments on 377 patients at our department during 2004. Larger sized treatment areas were the strongest pain predictor, and actinic keratoses were more painful to treat than basal cell carcinomas and Bowen’s disease. The most sensitive areas t ...
Pages: 545-551
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CLINICAL REPORT
Clinical Analysis of Skin Lesions in 796 Chinese HIV- positive Patients
Xiao-jie Huang, Hai-ying Li, De-xi Chen, Xi-cheng Wang, Zai-chun Li, Ya-song Wu, Tong Zhang, Yan-qing Gao, Hao Wu
Skin lesions are often associated with human immunodeficiency virus (HIV) infection, reflecting the immunocompromised status of the individual. We investigated the relationship between skin lesions and immune function in a retrospective study of 796 Chinese HIV patients with and without highly active antiretroviral therapy (HAART). Of the 651 patients who had not received HAART, we found that 531 ...
Pages: 552-556
Abstract  HTML  PDF
CLINICAL REPORT
High Prevalence of Mental Disorders and Emotional Distress in Patients with Chronic Spontaneous Urticaria
Petra Staubach, Markus Dechene, Martin Metz, Markus Magerl, Frank Siebenhaar, Karsten Weller, Peter Zezula, Annegret Eckhardt-Henn , Marcus Maurer
Quality of life, which is impaired in patients with chronic spontaneous urticaria (CSU), is influenced by comorbid mental disorders. The aim of this study was to assess the prevalence and spectrum of mental disorders and to determine levels of emotional distress in patients with CSU. One hundred patients with CSU were investigated for mental disorders (by specialized diagnostic interviews and psyc ...
Pages: 557-561
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CLINICAL REPORT
Systemic Rituximab in Multifocal Primary Cutaneous Follicle Centre Lymphoma
Gaëlle Quéreux, Anabelle Brocard, Lucie Peuvrel, Jean Michel Nguyen, Anne-Chantal Knol, Brigitte Dréno
The aim of this retrospective study was to assess the efficacy and tolerance of intravenous rituximab in multifocal primary cutaneous follicle centre lymphomas (PCFCL). Eleven patients with a multifocal PCFCL were treated with rituximab (MabThera®) administrated intravenously. After four infusions, an objective response was observed in 90% of patients, and one month after all the infusions (media ...
Pages: 562-567
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CLINICAL REPORT
Molecular Markers Associated with Clinical Response to Bexarotene Therapy in Cutaneous T-cell Lymphoma
Annamari Ranki, Liisa Väkevä, Laura Sipilä, Kai Krohn
Bexarotene (Targretin®), was registered for the treatment of cutaneous T-cell lymphoma (CTCL) in 2002, and has been reported to induce a 45% overall response. Responses are mostly partial or generate a stable, skin-restricted disease. This study explored the usefulness of a novel cancer-associated gene, NAV3 and corresponding chromosome 12 copy numbers as possible biomarkers to monitor the therap ...
Pages: 568-573
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CLINICAL REPORT
Atopic Dermatitis-like Pre-Sézary Syndrome: Role of Immuno­sup­pression
Małgorzata Sokołowska-Wojdyło, Wioletta Barańska-Rybak, Agnieszka Cegielska , Magdalena Trzeciak , Hanna Ługowska-Umer , Robert Gniadecki
We describe here 4 patients with Sézary syndrome masquerading as adult-onset atopic dermatitis. The patients presented with a clinical picture compatible with wide­spread atopic dermatitis and did not fulfil the criteria for Sézary syndrome (lack of lymphoadenopathy and blood involvement, skin histology without presence of atypical cells). In our patients, overt Sézary syndrome developed after ...
Pages: 574-577
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LETTER TO THE EDITOR
Pseudoleucoderma After Injections of Afamelanotide in a Patient with Atopic Dermatitis
Wibke von Bartenwerffer, Guido Siebenhaar, Nicolas Hunzelmann
Abstract is missing (Letter)
Pages: 578-579
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LETTER TO THE EDITOR
Cerebriform Plantar Hyperplasia: The Clinico-pathological Hallmark of Proteus Syndrome
Alessandro Di Stefani, Massimo Gabellini, Amedeo Ferlosio, Luigi Giusto Spagnoli, Sergio Chimenti, Augusto Orlandi
Abstract is missing (Letter)
Pages: 580-581
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LETTER TO THE EDITOR
Successful Use of Mizoribine in a Patient with Sarcoidosis and Cutaneous Vasculitis
Tamihiro Kawakami, Yoshinao Soma
Abstract is missing (Letter)
Pages: 582-583
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LETTER TO THE EDITOR
Paronychia and Pyogenic Granuloma Induced by New Anticancer mTOR Inhibitors
Vincent Sibaud, Florence Dalenc, Loic Mourey, Christine Chevreau
Abstract is missing (Letter)
Pages: 584-585
Abstract  HTML  PDF
LETTER TO THE EDITOR
Recurrent Subacute Cutaneous Lupus Erythematosus Following Exposure to Different Drugs
Aikaterini I. Liakou, Martina Brunner , Michael J. Theodorakis, Evgenia Makrantonaki, Christos C. Zouboulis
Abstract is missing (Letter)
Pages: 586-587
Abstract  HTML  PDF
LETTER TO THE EDITOR
Treatment of Pre-ulcerative Necrobiosis Lipoidica with Infliximab
Héléne Conte, Brigitte Milpied, Mamadou Kaloga, Nathalie Lalanne, Emilie Belin, Thomas Jouary, Alain Taieb, Khaled Ezzedine
Abstract is missing (Letter)
Pages: 587-588
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LETTER TO THE EDITOR
Acute Generalized Exanthematous Pustulosis due to Etodolac in a Patient with an Iliopsoas Muscle Abscess
Yoshitaka Nakamura, Akemi Takemoto, Masahiko Muto
Abstract is missing (Letter)
Pages: 589-590
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LETTER TO THE EDITOR
Onychomycosis: First Case Due to Aspergillus nomius
Mirca Zotti, Marco Machetti, Agostino Persi, Gianfranco Barabino, Aurora Parodi
Abstract is missing (Letter)
Pages: 591-592
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LETTER TO THE EDITOR
Tako-tsubo Cardiomyopathy after a Hymenoptera Sting and Treatment with Catecholamines
Nina Scheiba, Christiane Viedt-Suelmann, Knut Schäkel
Abstract is missing (Letter)
Pages: 593-594
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LETTER TO THE EDITOR
Severe Systemic Reaction to Topical Imiquimod
Anna-Kaisa Heikkinen, Päivikki Susitaival
Abstract is missing (Letter)
Pages: 594-595
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LETTER TO THE EDITOR
Anti-inflammatory Effects of Topical Formulations Containing Sea Silt and Sea Salt on Human Skin In Vivo During Cutaneous Microdialysis
Sven R. Quist, Ingrid Wiswedel , Jennifer Quist, Harald P. Gollnick
Abstract is missing (Letter)
Pages: 597-599
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LETTER TO THE EDITOR
Generalized Fixed Drug Eruption Caused by Pazufloxacin
Yu Sawada , Motonobu Nakamura, Yoshiki Tokura
Abstract is missing (letter)
Pages: 600-601
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LETTER TO THE EDITOR
A Case of Phacomatosis Pigmentokeratotica in Japanese Monozygotic Twins
Akiko Tara, Asuka Sada, Takuya Inoue, Noriyuki Misago, Yutaka Narisawa
Abstract is missing (letter)
Pages: 602-603
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LETTER TO THE EDITOR
Oral Mucous Membrane Pemphigoid: Complete Response to Topical Tacrolimus
Haur Yueh Lee, Claudia Blazek, Helmut Beltraminelli, Luca Borradori
Abstract is missing (letter)
Pages: 604-605
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LETTER TO THE EDITOR
Pruritus Differences Between Psoriasis and Lichen Planus
Adam Reich, Kalina Welz-Kubiak, Jacek C. Szepietowski
Abstract is missing (Letter)
Pages: 605-606
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QUIZ
A Pregnant Woman with a Nodule on the Tongue: A Quiz
Salvador Arias-Santiago, José Aneiros-Fernandez, Jacinto Orgaz-Molina, María Antonia Fernández-Pugnaire, Maria Sierra Girón-Prieto, Ramón Naranjo-Sintes, Jose Aneiros-Cachaza
Abstract is missing (Quiz)
Pages: 607-610
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QUIZ
A Hyperpigmented Plaque on the Right Nipple: A Quiz
Ying-chi Chen, Yi-Ju Chen, Chii-Shuenn Yang, Jui-Lung Shen
Abstract is missing (Quiz)
Pages: 607-610
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QUIZ
Red Papules on the Face: A Quiz
Tessin Watanabe, Masahisa Shindo, Yuichi Yoshida, Osamu Yamamoto
Abstract is missing (Quiz)
Pages: 607-610
Abstract  HTML  PDF