Content

Content - Volume 101, June

Editor's choice in this issue

INVESTIGATIVE REPORT
Choice of Systemic Drugs for the Management of Moderate-to-severe Psoriasis: A Cross-country Comparison Based on National Health Insurance Data
Emilie Sbidian, Myriam Mezzarobba, Jason Shourick, Cécile Billionnet, Joël Coste, Alain Weill, Jérémie Rudant, Olivier Chosidow, Loes Hollestein, Tamar Nijsten
Current management of moderate-to-severe psoriasis may be heterogeneous between European countries, probably due to differences in the organization of care. The aim of this study was to compare the utilization of systemic treatments for psoriasis between 2 coun­tries. All adults with psoriasis who were registered in the French (SNDS) and the Dutch (VEKTIS) national health insurance databases between 2012 and 2016 were eligible for inclusion. In France, 105,035 (15%) of 684,156 patients and, in the Netherlands, 37,405 (28.6%) of 130,822 patients received at least a systemic agent. In France, the proportion of patients treated with systemic agents was constant, while the type of drugs dispensed shifted from non-biological to biological agents. In the Netherlands, the first systemic treatment was methotrexate and, in France, acitretin. In France, the choice of the first biologic was much more variable than it was in the Netherlands, where a large proportion of patients were dispensed ustekinumab. This study highlights discrepancies between France and the Netherlands concerning the choice of first non-biologic agent and first biologic agent for patients with psoriasis. These discrepancies may be due to differences in the healthcare systems between the 2 countries.
Pages: 1-6
Abstract  HTML  PDF

All articles

SPECIAL REPORT
NEWSLETTER (June 2021)
Pages: 1-2
Abstract  PDF
SHORT COMMUNICATION
Inhibition of Transforming Growth Factor Beta and Immune Checkpoints Induces a Distinctively Distributed, Severe Bullous Pemphigoid
Soo Hyun Choi, Kyung Bae Chung, Do-Young Kim
Abstract is missing (Short communication)
Pages: 1-2
Abstract  HTML  PDF
CLINICAL REPORT
Relationship Between Tea Drinking Behaviour and Rosacea: A Clinical Case-control Study
Ben Wang, Bingbing Yan, Zhixiang Zhao, Yan Tang, Ying-xue Huang, Dan Jian, Wei Shi, Hongfu Xie, Yaling Wang, Ji Li
The exact mechanisms of rosacea development are unknown, but it has been suggested that tea consumption may be associated with its development. To determine the relationship between tea drinking behaviour and rosacea, this clinical case-control study recruited 2,063 participants, who completed a questionnaire about tea drinking behaviour. A 1:1 ratio propensity score matching method was used to ge ...
Pages: 1-7
Abstract  HTML  PDF
CLINICAL REPORT
Impact of Bariatric Surgery on Moderate to Severe Psoriasis: A Retrospective Nationwide Registry Study
Marta Laskowski, Linus Schiöler, Johan Ottosson, Marcus Schmitt-Egenolf, Ann-Marie Wennberg, Torsten Olbers, Kjell Torén, Helena Gustafsson
Studies of the effects of bariatric surgery on psoriasis are few, with conflicting results. By linking the Swedish National Register for Systemic Treatment of Psoriasis (PsoReg) with the Scandinavian Obesity Surgery Registry (SOReg), individuals with psoriasis who had undergone bariatric surgery in Sweden during 2008 to 2018 were identified, and matched with data for patients with psoriasis in Pso ...
Pages: 1-7
Abstract  HTML  PDF
SHORT COMMUNICATION
Sweet’s Syndrome Three Weeks after a Severe COVID-19 Infection: A Case Report
Simar Berro, Albane Calas, Pierre Sohier, Delphine Darbord, Nicolas Dupin
Abstract is missing (Short communication)
Pages: 1-2
Abstract  HTML  PDF
CLINICAL REPORT
Sunlight-induced Painful Skin (Sun Pain): A New Differential Diagnosis in Photodermatology
Piergiacomo Calzavara-Pinton, Marina Venturini, Chiara Rovati, Mariachiara Arisi, Irene Calzavara-Pinton, Fabrizio Rinaldi, Maria Teresa Rossi
Photodermatoses are characterized by the development of skin eruptions following exposure to ultraviolet radiation or visible light. We report here the clinical findings and results of laboratory investigations and phototesting of 6 patients who experience debilitating and excruciating pain after sun exposure (“sun pain”) in the absence of any skin eruption. Phototesting with sub-erythemal dos ...
Pages: 1-5
Abstract  HTML  PDF
SHORT COMMUNICATION
Paradoxical Reaction in a Patient with Hidradenitis Suppurativa Undergoing Adalimumab Treatment
Soichiro Ikeya, Takuya Takeichi, Tomoki Taki, Yoshinao Muro, Tomoo Ogi, Masashi Akiyama
Abstract is missing (Short Communication)
Pages: 1-2
Abstract  HTML  PDF
SHORT COMMUNICATION
Transient Increase in Circulating Basophils and Eosinophils in Dupilumab-associated Conjunctivitis in Patients with Atopic Dermatitis
Michie Katsuta, Yozo Ishiuji, Hiroyuki Matsuzaki, Ken-ichi Yasuda, Budiman Kharma, Yoshimasa Nobeyama, Takaaki Hayashi, Yoshiki Tokura, Akihiko Asahina
Abstract is missing (Short Commiunication)
Pages: 1-3
Abstract  HTML  PDF
CLINICAL REPORT
“I Feel I’m in Best Hands with You!”: A Survey of Patient Satisfac­tion in a German University Skin Cancer Centre
Theresa Steeb, Anja Wessely, Heike Merkl, Michael C. Kirchberger, Caroline Voskens, Michael Erdmann, Lucie Heinzerling, Carola Berking, Markus V. Heppt
An important measure of hospital quality is the satisfaction of patients. The aim of this cross-sectional study, performed in the dermato-oncology unit of the university hospital in Erlangen, Germany, was to assess skin cancer patients’ degree of satisfaction with healthcare services. Self-administered questionnaires on patient satisfaction regarding contact with staff, need for information, and ...
Pages: 1-7
Abstract  HTML  PDF
CLINICAL REPORT
Patients’ Perception of Vitiligo Severity
Nanja van Geel, Charlotte Moock, Marloes Zuidgeest, Sanne Elisabeth Uitentuis, Albert Wolkerstorfer, Reinhart Speeckaert
Identifying which factors contribute to vitiligo severity and determining their individual weight are important in the management of vitiligo. The aim of this study is to investigate the predictive variables concerning vitiligo severity as perceived by the patients. Based on a questionnaire, several factors that may contribute to the Patient Global Assessment (PtGA) of severity were investigated w ...
Pages: 1-6
Abstract  HTML  PDF
INVESTIGATIVE REPORT
An Ecological Study Indicates the Importance of Ultraviolet A Protection in Sunscreens
Samar Merhi, Pascale Salameh, Peter Kaplan, Shayak Banerjee, Mohamed Lajnef, Emmanuel L.P. Dumont, Khaled Ezzedine
The use of sunscreens is recommended to limit the impact of sun exposure on the skin. The objective of this study was to examine the relationship between sunscreen sales and melanoma in 4 different countries with diverse sunscreen regulations. Data from publicly avail­able databases were examined for Sweden, England, Australia, and the USA from 1999 to 2018. The association between incidence of m ...
Pages: 1-7
Abstract  HTML  PDF
INVESTIGATIVE REPORT
Altered Monocytic Phenotypes are Associated with Uraemic Pruritus in Patients Receiving Haemodialysis
Mei-Ju Ko, Wan-Chuan Tsai, Yu-Sen Peng, Shih-Ping Hsu, Mei-Fen Pai, Ju-Yeh Yang, Hon-Yen Wu, Yen-Ling Chiu
Uraemic pruritus is one of the most bothersome symptoms in patients receiving haemodialysis. A total of 175 patients receiving maintenance haemodialysis, with 74 patients experiencing uraemic pruritus, were prospectively recruited to assess the influence of the phenotype of blood monocytes and various cytokines on uraemic pruritus. The phenotype of blood monocytes was determined by flow cytometry ...
Pages: 1-6
Abstract  HTML  PDF
REVIEW
Locoregional Treatments for Digital Ulcers in Systemic Sclerosis: A Systematic Review
Ingrid Costedoat, Maeva Masson, Thomas Barnetche, Pierre Duffau, Estibaliz Lazaro, Christophe Richez, Julien Seneschal, Marie-Elise Truchetet
The management of digital ulcers in systemic sclerosis is difficult. While the 2017 European League Against Rheumatism (EULAR) guidelines clearly defined the use of systemic therapies for digital ulcers, little is known about the efficacy of locoregional treatments. The aim of this review is to systematically assess the spectrum of published locoregional therapies for digital ulcers. A total of 5 ...
Pages: 1-9
Abstract  HTML  PDF
INVESTIGATIVE REPORT
The Burden of Autosomal Recessive Congenital Ichthyoses on Patients and their Families: An Italian Multicentre Study
Damiano Abeni, Roberta Rotunno, Andrea Diociaiuti, Simona Giancristoforo, Domenico Bonamonte, Angela Filoni, Carmelo Schepis, Maddalena Siragusa, Iria Neri, Annalucia Virdi, Daniele Castiglia, Giovanna Zambruno, Christine Bodemer, May El Hachem
Autosomal recessive congenital ichthyoses (ARCI) are characterized by generalized skin scaling, hyperkeratosis, erythroderma, and disabling features affecting the skin (palmoplantar keratoderma, fissures, pain, itch), eyes, ears, and joints. Disease severity and chronicity, patient disfigurement, and time and costs required for care impose a major burden on quality of life. This multicentre cross- ...
Pages: 1-6
Abstract  HTML  PDF
INVESTIGATIVE REPORT
Patients with Darier Disease Exhibit Cognitive Impairment while Patients with Hailey-Hailey Disease Do Not: An Experimental, Matched Case-control Study
Philip Curman, Johanna Bern, Linnea Sand, Martin Cederlöf, Etty Bachar-Wikström, Jakob D. Wikström
Darier disease and Hailey-Hailey disease are severe, monogenetic dermatological disorders with mutations affecting all cells, making them liable to exhibit extra-dermal symptoms. The aim of this study is to assess broad cognitive function in individuals with these diseases, using an experimental, case-control set-up comparing cognition in patients with that in healthy controls matched for age, sex ...
Pages: 1-6
Abstract  HTML  PDF
SHORT COMMUNICATION
Therapeutic Inertia in the Management of Moderate-to-Severe Plaque Psoriasis in Adolescents
Audrey Melin, Jean-François Sei, Florence Corgibet, Cristèle Nicolas, Rémi Maghia, Bruno Halioua, Alain Beauchet, Emmanuel Mahé; and the Fédération Française de Formation Continue et d’Evaluation en Dermatologie-Vénéréologie
Abstract is missing (Short communication)
Pages: 1-3
Abstract  HTML  PDF
CLINICAL REPORT
Topical Application of Glycerol Increases Penetration Depth of Optical Coherence Tomography in Diagnosis of Basal Cell Carcinoma
Fieke Adan, Ellen M.M. Oyen, Robert J. Holtackers, Eva van Loo, Gert-Jan Dermont, Nicole W.J. Kelleners-Smeets, Patty J. Nelemans, Klara Mosterd
Optical coherence tomography is a non-invasive imaging technique that enables high-resolution in vivo imaging of skin. Although optical coherence tomography is promising for diagnosing basal cell carcinoma, its limited penetration depth may impede basal cell carcinoma subtyping. This study evaluated whether topical application of glycerol can increase penetration depth and improve the image qualit ...
Pages: 1-4
Abstract  HTML  PDF
INVESTIGATIVE REPORT
Choice of Systemic Drugs for the Management of Moderate-to-severe Psoriasis: A Cross-country Comparison Based on National Health Insurance Data
Emilie Sbidian, Myriam Mezzarobba, Jason Shourick, Cécile Billionnet, Joël Coste, Alain Weill, Jérémie Rudant, Olivier Chosidow, Loes Hollestein, Tamar Nijsten
Current management of moderate-to-severe psoriasis may be heterogeneous between European countries, probably due to differences in the organization of care. The aim of this study was to compare the utilization of systemic treatments for psoriasis between 2 coun­tries. All adults with psoriasis who were registered in the French (SNDS) and the Dutch (VEKTIS) national health insurance databases betw ...
Pages: 1-6
Abstract  HTML  PDF
SHORT COMMUNICATION
Ulcerated Lichen Planus after Adjuvant Use of Programmed Cell Death-1-Inhibitor: A Case Report and Systematic Review of the Literature
Anne-Charlotte Niesert, Anne Guertler, Olga Schutti, Laura Engels, Michael Flaig, Lars E. French, Max Schlaak, Markus Reinholz
Abstract is missing (Short communication)
Pages: 1-3
Abstract  HTML  PDF
SHORT COMMUNICATION
Impact of Bariatric Surgery on Hidradenitis Suppurativa
Clothilde Canard, Ana Diaz Cives, Isabelle Gaubil-Kaladjian, Eric Bertin, Manuelle Viguier
Abstract is missing (Short communication)
Pages: 1-3
Abstract  HTML  PDF
CLINICAL REPORT
Visual Impact of Large and Giant Congenital Naevi: Comparison of Surgical Scars with Naevi Before Surgery
Francesca Sampogna, Melinda González, Mirella Pascini-Garrigós, Neus Calbet-Llopart, Jennifer L. Hay, Bruce S. Bauer, Susana Puig, Josep Malvehy, Ashfaq A. Marghoob, Cristina Carrera
Surgical attempts to remove large/giant congenital melanocytic naevi (LGCMN) are supported mainly by the theoretical improvement in patients’ self-image; however such surgery can result in unaesthetic scarring. We hypothesize that difference in appearance itself has an impact, and hence surgery cannot negate this impact. The aim of this cross-sectional study was to explore how LGCMN and scarring ...
Pages: 1-7
Abstract  HTML  PDF
CLINICAL REPORT
Patient and Tumour Characteristics of Keratoacanthoma in a Large, Community-based Cohort Study from Queensland, Australia
Agnes Kolmodin, Nirmala P. Pandeya, Catherine M. Olsen, Jean Claude Dusingize, David C. Whiteman, Magdalena Claeson
Keratoacanthomas are common keratinocyte skin tumours. However, there is little community-based data published on the clinical features of keratoacanthoma. The aim of this study was to describe the patient and tumour characteristics of keratoacanthomas, as well as their treatment patterns. Data were obtained from the QSkin Sun and Health study, a prospective cohort of 40,438 randomly sampled and c ...
Pages: 1-7
Abstract  HTML  PDF