Content

Content - Volume 87, Issue 4

Editor's choice in this issue

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IN THIS ISSUE
Itching for Clarification
Jonathan L. Rees
Section Editor
Pages: 290-290
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SPECIAL REPORT
Clinical Classification of Itch: a Position Paper of the International Forum for the Study of Itch
Sonja Ständer, Elke Weisshaar, Thomas Mettang, Jacek C. Szepietowski, Earl Carstens, Akihiko Ikoma, Nora V. Bergasa, Uwe Gieler, Laurent Misery, Joanna Wallengren, Ulf Darsow, Markus Streit, Dieter Metze, Thomas A. Luger, Malcolm W. Greaves, Martin Schmelz, Gil Yosipovitch and Jeffrey D. Bernhard
Chronic itch is a common and distressing symptom that arises from a variety of skin conditions and systemic diseases. Despite this, there is no clinically based classification of pruritic diseases to assist in the diagnosis and cost-effective medical care of patients with pruritus. The proposed classification focuses on clinical signs and distinguishes between diseases with and without primary or ...
Pages: 291-294
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REVIEW
Nocturnal Itch: Why Do We Itch At Night?
Tejesh Patel, Yozo Ishiuji and Gil Yosipovitch
Pruritus is exacerbated at night in many systemic and dermatological diseases, resulting in reports of significantly diminished quality of life and sleep disturbances. At present, the underlying mechanisms responsible for night-time itching are not well understood. Nocturnal pruritus may be related to the circadian rhythm of itch mediators and possibly the disruption of such patterns. Diurnal chan ...
Pages: 295-298
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INVESTIGATIVE REPORT
Plasma Neuropeptides and Perception of Pruritus in Psoriasis
Adam Reich, Alina Orda, Beata Wisnicka and Jacek C. Szepietowski
The aim of this study was to evaluate the influence of selected neuropeptides on itching in psoriatic individuals. Fifty-nine patients (43 pruritic and 16 non-pruritic) with psoriasis were included in the study. The severity of psoriasis, measured using the Psoriasis Area and Severity Index scale, ranged between 2 and 43.7 points. The intensity of pruritus was evaluated using a Visual Analogue Sca ...
Pages: 299-304
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INVESTIGATIVE REPORT
Differential Immunomodulating Effects of Inactivated Probiotic Bacteria on the Allergic Immune Response
Claudia Rasche, Christin Wolfram, Michael Wahls and Margitta Worm
Bacterial stimulation plays an important role in modu­lating the allergic immune response. The aim of this study was to investigate the effects of inactivated probiotic Lacto­bacillus acidophilus and non-pathogenic Escherichia coli strain Nissle on the phenotype and function of T- and B-cells. Peripheral blood mononuclear cells from patients with grass-pollen allergy (n = 10) and non-allergi ...
Pages: 305-311
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INVESTIGATIVE REPORT
Evaluation of Phototoxic Properties of Fragrances
Marianne Placzek, Wolfgang Frömel, Bernadette Eberlein, Klaus-Peter Gilbertz and Bernhard Przybilla
Fragrances are widely used in topical formulations and can cause photoallergic or phototoxic reactions. To identify phototoxic effects, 43 fragrances were evaluated in vitro with a photohaemolysis test using suspensions of human erythrocytes exposed to radiation sources rich in ultraviolet (UV) A or B in the presence of the test compounds. Haemolysis was measured by reading the absorbance values, ...
Pages: 312-316
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INVESTIGATIVE REPORT
How Do Personality Systems Interact in Patients With Psoriasis, Atopic Dermatitis and Urticaria?
Judith A. Bahmer, Julius Kuhl and Friedrich A. Bahmer
The aim of this study was to evaluate characteristic personality system interaction in patients with psoriasis, atopic dermatitis and urticaria. The differences between these three disease groups were examined with respect to various psychological variables and deviations from a group of healthy controls. A total of 56 patients with atopic dermatitis (n=21), psoriasis (n=20) and urticaria (n=15) w ...
Pages: 317-324
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CLINICAL REPORT
Photodynamic Therapy for Acne Vulgaris: a Pilot Study of the Dose-Response and Mechanism of Action
Camilla Hörfelt, Bo Stenquist, Olle Larkö, Jan Faergemann and Ann-Marie Wennberg
Acne vulgaris does not always respond to conventional therapy. Photodynamic therapy (PDT) has been proposed as a treatment option. The aim of this study was to determine the optimal light dose for effective PDT treatment of acne and to investigate whether PDT reduces sebum excretion and the amount of Propionibacterium acnes. Fifteen patients (9 men, 6 women, age range 16–44 years, mean age 25 ye ...
Pages: 325-329
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CLINICAL REPORT
Factors Affecting the Recurrence Rate of Basal Cell Carcinoma
Fie Saabye Bøgelund, Peter Ashlede Philipsen and Robert Gniadecki
The aim of this retrospective survey was to determine recurrence rates after treatment of basal cell carcinomas in a single academic dermatology department. A total of 1016 patients with 1593 histologically verified basal cell carcinomas (n=1212 primary and n=381 relapsing) were included. Tumour localization, T-stage and the method of treatment were significant predictors of the risk of recurrence ...
Pages: 330-334
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INVESTIGATIVE REPORT
Comparison of Clinical Features of HLA-Cw*0602-Positive and -Negative Psoriasis Patients in a Han Chinese Population
Xing Fan, Sen Yang, Liang Dan Sun, Yan Hua Liang, Min Gao, Kai Yue Zhang, Wei Huang and XueJun Zhang
HLA-Cw6 is strongly associated with psoriasis and has been suggested to be the PSORS1 gene that confers susceptibility to early-onset psoriasis. In this study of the clinical features of HLA-Cw*0602-positive and -negative psoriasis patients in a Han Chinese population, we typed HLA-C in a cohort of 679 patients and compared the two groups. Cw*0602-positive patients (n=345) had an earlier disease o ...
Pages: 335-340
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CLINICAL REPORT
Functional Itch Disorder or Psychogenic Pruritus: Suggested Diagnosis Criteria From the French Psychodermatology Group
Laurent Misery, Sophie Alexandre, Sabine Dutray, Myriam Chastaing, Sylvie G. Consoli, Hubert Audra, Domitille Bauer, Sylviane Bertolus, Valérie Callot, Fabienne Cardinaud, Eliane Corrin, Nathalie Feton-Danou, Robert Malet, Sylviane Touboul and Silla M. Consoli
"Functional itch disorder or psychogenic pruritus is a poorly defined diagnosis. This paper sets out the proposed diagnostic criteria of the French Psychodermatology Group (FPDG). There are three compulsory criteria: localized or generalized pruritus sine materia, chronic pruritus (>6 weeks) and the absence of a somatic cause. Three additional criteria from the following seven items should also be ...
Pages: 341-344
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CLINICAL REPORT
Quality of Life in Swedish Children with Eczema
Agneta Gånemo, Åke Svensson, Magnus Lindberg and Carl-Fredrik Wahlgren
The burdens of childhood eczema are many and some can be assessed with quality of life (QoL) questionnaires. Seventy-eight Swedish children with mild-to-severe eczema (“atopic dermatitis”, prurigo Besnier), fulfilling established diagnostic criteria, were investigated for the effect of eczema on QoL. This was measured with validated questionnaires: the Infants' Dermatitis Quality of Life Index ...
Pages: 345-349
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CLINICAL REPORT
Vulvar Vestibulitis and Risk Factors: a Population-based Case-control Study in Oslo
Karin Edgardh and Michael Abdelnoor
Vulvar vestibulitis is a major cause of entry dyspareunia in young women. The aim of this study was to evaluate a self-reported history of bacterial vaginosis, candidiasis, use of oral contraception and nulli-pregnancy as risk factors for vestibulitis. A retrospective examination of medical records was performed for 45 patients with vestibulitis from a vulvar clinic in Oslo, median age 24 years, a ...
Pages: 350-354
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CLINICAL REPORT
Herpes Simplex Virus Infection and Genital Ulcer Disease Among Patients with Sexually Transmitted Infections in Dar es Salaam, Tanzania
Arvid Nilsen, Mabula Joseph Kasubi, Stein Christian Mohn, Davis Mwakagile, Nina Langeland and Lars Haarr
"The relative importance of Haemophilus ducreyi and Treponema pallidum in genital ulcer disease in Africa has decreased recently, whereas that of herpes simplex virus (HSV) type 2 has increased. We analysed 301 lesional specimens from Tanzanian patients with genital ulcer disease for the presence of H. ducreyi, T. pallidum and HSV-1/HSV-2 by performing a separate PCR for each pathogen. Infectious ...
Pages: 355-359
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LETTER TO THE EDITOR
Diffuse and Aggressive Cutaneous Granulomatosis Revealing a Cytotoxic Cell Systemic Lymphoma
Virginie de Schaetzen1, Valérie Costes2, Bernard Guillot1 and Olivier Dereure1*
This article does not have an abstract.
Pages: 361-363
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LETTER TO THE EDITOR
Coexistence of Linear Porokeratosis and Disseminated Superficial Actinic Porokeratosis: A Type 2 Segmental Manifestation
Oscar Suárez-Amor, Mercedes Pereiro-Ferreirós, Manuel Ginarte, Carmen Peteiro and Jaime Toribio
This article does not have an abstract.
Pages: 363-364
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LETTER TO THE EDITOR
Vegetative Pyoderma Gangrenosum in Behçet’s Disease
Jung-Wook Kim, Jeong-Hoon Park, Deborah Lee, Seon-Wook Hwang and Sung-Wook Park
This article does not have an abstract.
Pages: 365-367
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LETTER TO THE EDITOR
Genital Graft-versus-host Disease in a Male Following Allogeneic Stem Cell Transplantation
Elisabet Nylander1, Ylva Britt Wahlin2, Bertil Lundskog3 and Anders Wahlin4
This article does not have an abstract.
Pages: 367-368
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LETTER TO THE EDITOR
Does Thrombosis Cause Intravascular Fasciitis?
Makoto Sugaya and Kunihiko Tamaki
This article does not have an abstract.
Pages: 369-370
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LETTER TO THE EDITOR
Low Incidence of Polymorphous Light Eruption in Renal Transplant Recipients
Bouteina Benanni1, Thomas Bruckner3, Michael Bock3, Brigitte Faivre1, Jean Michel Rebibou2, Thomas Diepgen3, Philippe Humbert1 and François Aubin1*
This article does not have an abstract.
Pages: 372-374
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LETTER TO THE EDITOR
Subcutaneous Sarcoidosis with Sarcoidal Polyneuropathy
Tessin Watanabe, Yuichi Yoshida and Osamu Yamamoto
This article does not have an abstract.
Pages: 374-375
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LETTER TO THE EDITOR
Rosai-Dorfman Disease and Granuloma Annulare
Isabelle Marie1, Eva Verdier1, Philippe Courville2, Alain Manrique3, Thierry Ducastelle4, Pascal Joly5 and Hervé Levesque1
This article does not have an abstract.
Pages: 375-377
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LETTER TO THE EDITOR
Pompholyx Eczema as a Manifestation of HIV Infection, Response to Antiretroviral Therapy
Alisdair A. MacConnachie* and Catherine C. Smith
This article does not have an abstract.
Pages: 378-379
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LETTER TO THE EDITOR
Detection of Treponema pallidum DNA in the Serum of an Adequately Treated Patient with Latent Syphilis
Vladana Woznicová and Monika Heroldová
This article does not have an abstract.
Pages: 379-380
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LETTER TO THE EDITOR
Erythema Multiforme-like Targetoid Lesions in Secondary Syphilis
Yoon Young Kim, Ji Hyun Lee, Sun Yeong Yoon, Jeong Deuk Lee and Sang Hyun Cho*
This article does not have an abstract.
Pages: 381-382
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