Content

Content - Volume 100, April

Editor's choice in this issue

CLINICAL REPORT
Subjective and Objective Characteristics of Patients Seen at a Psychodermatology Unit: One-year Experience in Malmö, Sweden
Florence J. Dalgard, Karin Sjöström, Johan Fhager, Åke Svensson, Ewa Wallin, Inese Hauksson
We performed this study because a substantial number of dermatological patients are in need of psychodermatological services, yet knowledge is scarce on the morbidity of this patient population. We recently initiated a psychodermatology unit in the department of dermatology in Malmö and systematically screened all our patients. The simplicity and originality of our present study is that we report the morbidity from our patients’ perspective as well as from a dermatological and psychiatric perspective. These combined perspectives enable us to get a whole picture of this patient group and inspire others to organize and improve adequate services in dermatological departments.
Pages: 1-6
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SHORT COMMUNICATION
Cutaneous Clinico-Pathological Findings in three COVID-19-Positive Patients Observed in the Metropolitan Area of Milan, Italy
Raffaele Gianotti, Stefano Veraldi, Sebastiano Recalcati, Marco Cusini, Massimo Ghislanzoni, Francesca Boggio, Lindy P. Fox
Milan has been struck down by a dramatic outbreak caused by COVID-19, with numerous infected people and deaths. One possible reason is the high number of elderly people as well as the high median age of the population. However, this outbreak is a good opportunity for dermatologists to improve their knowhow in the field of clinical virology. In fact, COVID-19 is characterized by numerous different clinical presentations on the skin. Erythematous rash, papular-vesicular eruptions, urticaria and acral ischemic lesions seem to be the most frequent manifestations. Our study is a preliminary approach to this topic. We hope it is useful for all dermatologists involved in the management of this outbreak.
Pages: 1-2
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All articles

SPECIAL REPORT
NEWSLETTER (APRIL 2020)
Pages: 1-3
Abstract  PDF
CLINICAL REPORT
Actinic Keratosis Diagnosis and Increased Risk of Developing Skin Cancer: A 10-year Cohort Study of 17,651 Patients in Sweden
Ghassan Guorgis, Chris D. Anderson, Johan Lyth, Magnus Falk
Actinic keratosis is the most common actinic lesion in fair-skinned populations. It is accepted as an indicator of actinic skin damage and as an occasional precursor of squamous cell carcinoma. The aim of this study was to investigate, in a cohort of patients with a diagnosis of actinic keratosis, the relative risk of developing skin cancer during a follow-up period of 10 years. This registry-base ...
Pages: 1-6
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SHORT COMMUNICATION
Prevalence of Indoor Tanning Among Teenagers in Norway Before and After Enforcement of Ban for Ages Under 18 Years
Trude E. Robsahm, Jo S. Stenehjem, Leon A.M. Berge, Marit B. Veierød
Abstract is missing (Short communication)
Pages: 1-2
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CLINICAL REPORT
Subjective and Objective Characteristics of Patients Seen at a Psychodermatology Unit: One-year Experience in Malmö, Sweden
Florence J. Dalgard, Karin Sjöström, Johan Fhager, Åke Svensson, Ewa Wallin, Inese Hauksson
Clinical epidemiological knowledge concerning psychodermatology patients is scarce. The objective of this study was to assess morbidity in a new psychodermatology service. Information was gathered from patient records at the psychodermatology unit in Skåne University Hospital, Malmö, Sweden, from 1 February 2017 to 31 January 2018. All patients were screened with the Hospital Anxiety and Depress ...
Pages: 1-6
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CLINICAL REPORT
Short-term Effect and Acceptability of Manual Lymphatic Drainage for Paediatric Limb Lymphoedema: A Prospective Study
Chakib El Habnouni, Valérie Tauveron, Sophie Leducq, Stéfania Gérémia, Pierre Allain, Hortense Touchard, Sophie-Anne Benejean, Laurent Machet, Annabel Maruani
Paediatric lymphoedema (LE) is a rare condition, for which there is little data available regarding treatments. The aim of this study was to assess the short-term effect and acceptability of a 30-min session of manual lymphatic drainage (MLD) in children with well-documented LE of the lower limbs. Fifteen children were included (8 males; median age 11 years). Comparison of the sum of circumference ...
Pages: 1-5
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SHORT COMMUNICATION
Cutaneous Clinico-Pathological Findings in three COVID-19-Positive Patients Observed in the Metropolitan Area of Milan, Italy
Raffaele Gianotti, Stefano Veraldi, Sebastiano Recalcati, Marco Cusini, Massimo Ghislanzoni, Francesca Boggio, Lindy P. Fox
Abstract is missing (Short communication)
Pages: 1-2
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SHORT COMMUNICATION
Inflammatory Vegetative Lesions of the Perineum: A Rare and Severe Clinical Presentation of Netherton Syndrome
Shatha Albluwi, Aude Maza, Maella Severino-Freire, Emilie Tournier, Juliette Mazereeuw-Hautier
Abstract is missing (Short communication)
Pages: 1-2
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INVESTIGATIVE REPORT
Psoriatic Dermal-derived Mesenchymal Stem Cells Reduce Keratinocyte Junctions, and Increase Glycolysis
Junqin Li, Jianxiao Xing, Funa Lu, Wenjuan Chang, Nannan Liang, Juan Li, Ying Wang, Xiaofang Li, Xincheng Zhao, Ruixia Hou, Maoqiang Man, Guohua Yin, Xinhua Li, Kaiming Zhang
Although it is known that psoriatic dermal-derived mesenchymal stem cells (DMSCs) dysregulate keratinocyte proliferation, the biological activity profile of keratinocytes influenced by psoriatic DMSCs remain unknown. In the present study, we assessed the impact of psoriatic DMSCs on keratinocyte proliferation, differentiation, and glucose metabolism in normal human epidermal keratinocytes co-cultu ...
Pages: 1-7
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INVESTIGATIVE REPORT
Recurrent and Metastatic Cutaneous Squamous Cell Carcinomas in a Cohort of 774 Patients in Finland
Niina Korhonen, Leea Ylitalo, Tiina Luukkaala, Julius Itkonen, Henni Häihälä, Juha Jernman, Erna Snellman, Johanna Palve
Recognising patients with high risk cutaneous squamous cell carcinomas is essential in planning effective monitoring. The aim of this study was to determine the rate of local recurrences and metastases of cutaneous squamous cell carcinomas in a previously defined patient cohort in Finland. Pathology database search was performed to identify cutaneous squamous cell carcinoma patients and their medi ...
Pages: 1-3
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CLINICAL REPORT
Exploring the EQ-5D Dimension of Pain/Discomfort in Dermatology Outpatients from a Multicentre Study in 13 European Countries
Francesca Sampogna, Damiano Abeni, Uwe Gieler, Lucía Tomas Aragones, Lars Lien, Françoise Poot, Gregor B. E. Jemec, Csanád Szabó, Dennis Linder, Henriët van Middendorp, Jon Anders Halvorsen, Flora Balieva, Jacek C. Szepietowski, Dmitry V. Romanov, Servando E. Marron, Ilknur K. Altunay, Andrew Y. Finlay, Sam S. Salek, Jörg Kupfer, Laurent Misery, Florence J. Dalgard
Pain and discomfort are important symptoms in dermatology. The aim of this cross-sectional, multicentre study was to describe the prevalence of pain/discomfort and its associations in patients with several dermatological conditions across 13 European countries. The outcome was the prevalence of pain/discomfort according to a question of the EQ-5D questionnaire. Data collected from November 2011 to ...
Pages: 1-6
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CLINICAL REPORT
Treatment and Burden of Disease in a Cohort of Patients with Prurigo Nodularis: A Survey-based Study
Tanja Todberg, Claus Zachariae, Lone Skov
Prurigo nodularis is a pruritic dermatosis with poor treatment options. To describe treatment patterns, comorbidities, pruritus, and quality of life a survey was administered to 92 patients with prurigo nodularis. A total of 52 patients completed the survey. The most frequently used treatments were topical corticosteroids, which were prescribed to 49/52 patients, with positive effect in 13/49. A t ...
Pages: 1-5
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SHORT COMMUNICATION
Efficacy of Apremilast in Patients with Prurigo Nodularis: A Proof-of-concept Study
Tanja Todberg, Lone Skov, Stine Simonsen, Kati Kainu, Claus Zachariae
Abstract is missing (Short communication)
Pages: 1-2
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INVESTIGATIVE REPORT
Patient Satisfaction and Expectations Regarding Mobile Teledermoscopy in General Practice for Diagnosis of Non-melanoma Skin Cancer and Malignant Melanoma
Sofie Gilling, Charlotte G. Mortz, Tine Vestergaard
The incidence of non-melanoma skin cancer and malignant melanoma is increasing. Diagnosing these skin lesions is primarily done visually, making it suitable to use new technology, such as teledermoscopy. Before the implementation of teledermoscopy, patient satisfaction, clinician satisfaction and diagnostic accuracy, need to be evaluated. A cross-sectional quantitative survey was conducted to eval ...
Pages: 1-7
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REVIEW
Direct Costs of Epidermolysis Bullosa by Disease Severity
Darragh Flannery, Claire Doyle, Sineád Hickey, Fiona Aherne, Avril Kennan
Abstract is missing (Short communication)
Pages: 1-2
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QUIZ
Linear Blisters in a Young Girl: A Quiz
Weilong Zhong, Xingling Jian, Shangzhi Dai, Xuejun Zhu, Zhimiao Lin, Bo Yu
Abstract is missing (Quiz)
Pages: 1-3
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INVESTIGATIVE REPORT
Guanine Deaminase Stimulates Ultraviolet-induced Keratinocyte Senescence in Seborrhoeic Keratosis via Guanine Metabolites
Kyung Ah Cheong, Ai-Young Lee
DNA damage and oxidative stress play a critical role in photoageing. Seborrhoeic keratosis (SK) affects sunlight-exposed sites in aged individuals. This study examined the mechanism of photoageing in SK. The guanine deaminase gene, which is involved in purine metabolism, was upregulated with uric acid levels and p21 in SK. Guanine deaminase was detectable in keratinocytes. Repeated exposure to ult ...
Pages: 1-10
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SHORT COMMUNICATION
Refractory bullous pemphigoid improved by discontinuation of phenytoin as an CYP3A4 inducer
Rei Yokoyama, Ryota Hayashi, Yukie Umemori, Ami Arimatsu, Akihiko Yuki, Riichiro Abe
Abstract is missing (Short communication)
Pages: 1-2
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CLINICAL REPORT
Body Image Quality of Life in Patients with Hidradenitis Suppurativa Compared with Other Dermatological Disorders
Pernille Lindsø Andersen, Rikke Maria Nielsen, Viktoria Sigsgaard, Gregor B. E. Jemec, Peter T. Riis
Hidradenitis suppurativa is a chronic skin disease characterized by inflammation and disfiguring scarring in the intertriginous body areas. Hidradenitis suppurativa is associated with overweight and impaired quality of life. This study sought to describe Body Image Quality of Life (BI-QoL) in patients with hidradenitis suppurativa and to compare it with patients with other skin diseases (controls) ...
Pages: 1-6
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CLINICAL REPORT
Microblotches on Dermoscopy of Melanocytic Lesions are Associated with Melanoma: A Cross-sectional Study
Vania Lukoviek, Nuria Ferrera, Sebastian Podlipnik, Sümeyre Seda Ertekin, Cristina Carrera, Alicia Barreiro, Marion Chavez-Bourgeois, Francesca Perino, Mauricio Ortiz-Ruiz, Susana Puig, Josep Malvehy
Numerous dermoscopic structures for the early detection of melanoma have been described. The aim of this study was to illustrate the characteristics of dermoscopic structures that are similar to blotches, but smaller (termed microblotches), and to evaluate their association with other well-known dermoscopic structures. A cross-sectional study design, including 165 dermoscopic images of melanoma wa ...
Pages: 1-4
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INVESTIGATIVE REPORT
“DLQI Seems to be ‘Action’, and Skindex-29 Seems to be ‘Emotion’”: Qualitative Study of the Perceptions of Patients with Psoriasis or Eczema on Two Common Dermatology-specific Quality of Life Measures
Priyamvada Paudyal, Christian Apfelbacher, Christina Jones, Sanna Siddiqui, Aisha El-Turki, Claudia DeGiovanni, Helen Smith
Little is known about which quality of life measure best captures the lived experience of people with a chronic skin condition. The purpose of this study was to explore patients’ views on the Dermatology Life Quality Index (DLQI) and Skindex-29. Participants were adults (n = 28) with a diagnosis of eczema or psoriasis who completed the DLQI and the Skindex-29 before being interviewed about t ...
Pages: 1-6
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QUIZ
Bilateral Alopecia in a Six-year-old Boy: A Quiz
Sarah Ventéjou, Marie-Anne Morren, Kimberley George, Maxime Vernez, Daniel Hohl, Stephanie Christen-Zäch
Abstract is missing (Quiz)
Pages: 1-2
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SHORT COMMUNICATION
Oculoectodermal Syndrome – Encephalocraniocutaneous Lipomatosis Associated with NRAS Mutation
Renée J.H. Richters, Marieke M.B. Seyger, Kim A.P. Meeuwis, Tuula Rinne, Astrid Eijkelenboom, Michèl A. Willemsen
Abstract is missing (Short communication)
Pages: 1-2
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