Content

Content - Volume 100, June

Editor's choice in this issue

CLINICAL REPORT
Clinical and Ultrasonographic Profile of Adalimumab-treated Hidradenitis Suppurativa Patients: A Real-life Monocentric Experience
Andrea Chiricozzi, Giulia Giovanardi, Simone Garcovich, Dalma Malvaso, Giacomo Caldarola, Barbara Fossati, Cristina Guerriero, Clara De Simone, Ketty Peris
The use of ultrasonography (US) is becoming increasingly common in supporting diagnosis and treatment of hidradenitis suppurativa (HS). The main goal of this study was to correlate clinical evaluation with US findings, identifying markers that could predict a positive or negative response to adalimumab therapy. Disease duration was the most relevant clinical variable affecting disease severity and treatment response, highlighting the importance of both a timely diagnosis and a prompt therapy. Additionally, the subcutaneous involvement of HS lesions detected by US was associated with significantly lower response to therapy, constituting one negative predictive factor to adalimumab response.
Pages: 1-6
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All articles

SPECIAL REPORT
NEWSLETTER (June 2020)
Pages: 1-3
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QUIZ
Dark Lesion with Irregular and Polymorphous Vascularization in Two Patients: A Quiz
Carmen Couselo-Rodríguez, Laura Mesa-Álvarez, Hae Jin Suh-Oh, Carlos Álvarez, Ángeles Flórez
Abstract is missing (Quiz)
Pages: 1-2
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SHORT COMMUNICATION
Giant Superficial Basal Cell Carcinoma Diagnosed and Treated as Psoriasis: Report of Two Cases and a Literature Review
Iwona Chlebicka, Beata Jastrząb, Aleksandra Stefaniak, Anita Hryncewicz-Gwóźdź, Jacek C. Szepietowski
Abstract is missing (Short communication)
Pages: 1-2
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SHORT COMMUNICATION
LAight® Therapy Improves Hidradenitis Suppurativa in Patients Declining Surgical Intervention: Two Case Reports
Izak Johannes Bisschoff, Daniela Kasche, Uwe Kirschner, Piotr K. Krajewski, Łukasz Matusiak, Jacek C. Szepietowski
Abstract is missing (Short communication)
Pages: 1-2
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SHORT COMMUNICATION
Hydroa Vacciniforme-like Lymphoproliferative Disorder Treated with Intravenous Immunoglobulin: Long-term Remission Without Haematopoietic Stem Cell Transplantation or Chemotherapy
YePing Ruan, XiaoYan Shen, Ruofei Shi, XiaoQing Zhao, Jie Zheng
Abstract is missing (Short communication)
Pages: 1-2
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SHORT COMMUNICATION
Massive Acute Alopecia of the Scalp in a Patient Treated with Dupilumab
Rosella Gallo, Ilaria Trave, Aurora Parodi
Abstract is missing (Short communication)
Pages: 1-2
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QUIZ
Acquired Wrinkled Plaques: A Quiz
Caroline de Lorenzi, Sandra Leoni-Parvex, Carlo Mainetti
Abstract is missing (Quiz)
Pages: 1-2
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REVIEW
Effect of Patient Characteristics on Treatment Decisions Regarding Keratinocyte Carcinoma in Elderly Patients: A Review of the Current Literature
Marjolijn S. Haisma, Linda Bras, Mehran Alizadeh Aghdam, Jorrit B. Terra, Boudewijn E.C. Plaat, Emöke Rácz, Gyorgy B. Halmos
There are straightforward guidelines for treatment of keratinocyte carcinoma (formerly known as non-melanoma skin cancer); however, there are no clear recommendations specifically for elderly patients. The aim of this review was to provide an overview of the current literature about the effect of patient characteristics, specifically life expectancy, frailty and comorbidity, on treatment decisions ...
Pages: 1-7
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CLINICAL REPORT
Clinicopathological Factors Associated with Incomplete Excision of Cutaneous Squamous Cell Carcinoma
Helena Svensson, John Paoli
Cutaneous squamous cell carcinoma (SCC) is the second most common type of cancer in Swedish men and women. The incidence of SCC is increasing rapidly. Primary treatment is complete surgical excision with sufficient margins to avoid recurrence and metastasis. The aim of this retrospective study was to identify the clinicopathological factors associated with incomplete excision of SCCs. Clinicopatho ...
Pages: 1-5
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CLINICAL REPORT
Pilot Study of a Novel Therapeutic Approach for Refractory Advanced Stage Folliculotropic Mycosis Fungoides
Christina A. Del Guzzo, Neha N. Jariwala, Paul L. Haun, Kelly M. MacArthur, Christen M. Mowad, Elisabeth G. Richard, Joseph P. Holton, Alain H. Rook
Folliculotropic mycosis fungoides is a variant of cutaneous T-cell lymphoma characterized as having a folliculocentric infiltrate of malignant T cells along with a worse prognosis in comparison to the epidermotropic variants. Patients with advanced forms of folliculotropic mycosis fungoides are often poorly responsive to both skin-directed as well as to systemic therapies. We report here a high re ...
Pages: 1-5
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QUIZ
Psoriasiform Lesions on the Palms and Soles: A Quiz
Lan Zhang, Yang Yang, Song Zheng, Xinghua Gao, Li Zhang
Abstract is missing (Quiz)
Pages: 1-2
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QUIZ
Reddish Smooth Nodule on the Labia Majora: A Quiz
Miyuki Yamamoto, Toshiyuki Yamamoto
Abstract is missing (Quiz)
Pages: 1-2
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QUIZ
Red Nodule in a Post-surgical Scar: A Quiz
Piotr K. Krajewski, Iwona Chlebicka, Kinga Tyczyńska, Jacek C. Szepietowski
Abstract is missing (Quiz)
Pages: 1-3
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CLINICAL REPORT
Implication of Perifollicular Clusters and Folliculotropic Distribution of Dendritic Cells in the Pathogenesis of Seborrhoeic Dermatitis
Ayako Ito, Kazunari Sugita, Hiroyuki Goto, Osamu Yamamoto
The pathogenesis of seborrhoeic dermatitis is controversial and remains unclear. Malassezia is considered to be a commensal fungi and is found not only in the stratum corneum but also in hair follicles. It is an important pathogenic factor in seborrhoeic dermatitis. The aim of this study was to clarify the pathogenesis of seborrhoeic dermatitis, morphologically, through comparison with psoriasis v ...
Pages: 1-6
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SHORT COMMUNICATION
Annular Sarcoidosis with Geographic Appearance in a Patient with Systemic Sarcoidosis
Hiroyuki Takama, Yuichiro Ohshima, Yoriko Ando, Takeshi Yanagishita, Emiko Takahashi, Toyonori Tsuzuki, Keisuke Uchida, Yoshinobu Eishi, Masashi Akiyama, Daisuke Watanabe
Abstract is missing (Short communication)
Pages: 1-2
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SHORT COMMUNICATION
Adenovirus-induced Erythema Multiforme: Eye and Genital Mucosal Involvement is Specific, Whereas Oral and Cutaneous Involvement is Not
Albane Calas, Coralie Lheure, Charlotte Bernigaud, Jean-François Meritet, Pierre Sohier, Jérémy Augustin, Camille Isnard, Nathalie Franck, Gerard Royer, Saskia Ingen-Housz-Oro, Nicolas Dupin
Abstract is missing (Short communication)
Pages: 1-2
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SHORT COMMUNICATION
Infantile Lipofibromatosis-like Neural Tumour Investigated by a Fusion Gene Detection Assay
Hiromi Higaki-Mori, Masanori Hisaoka, Yuichi Yoshida, Yuko Ehara, Masahisa Shindo, Osamu Yamamoto
Abstract is missing (Short communication)
Pages: 1-2
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SHORT COMMUNICATION
Secondary Intention Healing After Functional Surgery for in Situ or Minimally Invasive Nail Melanoma
Gwanghyun Jo, Keunyoung Hur, Soo Ick Cho, Je-Ho Mun
Abstract is missing (Short communication)
Pages: 1-2
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SHORT COMMUNICATION
Acquired Haemophilia A in DPP4 Inhibitor-induced Bullous Pemphigoid as Immune Reconstitution Syndrome
Seiko Sugiyama, Ryota Tanaka, Hiroaki Hayashi, Kentaro Izumi, Wataru Nishie, Yumi Aoyama
Abstract is missing (Short communication)
Pages: 1-2
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QUIZ
Ulcerative Pigmented Nodules on a Postoperative Scar: A Quiz
Hiroyuki Goto, Yuichi Yoshida, Osamu Yamamoto
Abstract is missing (Quiz)
Pages: 1-2
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SHORT COMMUNICATION
Occupational Skin Cancer in a Crematory Operator
Gabriella Fredman, Maria Blomberg, Ulrikke Lei
Abstract is missing (Short communication)
Pages: 1-2
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INVESTIGATIVE REPORT
Psychological Consequences of the Most Common Dermatoses: Data from the Objectifs Peau Study
Laurent Misery, Charles Taïeb, Martine Schollhammer, Sylviane Bertolus, Eva Coulibaly, Nathalie Feton-Danou, Laurence Michel, Jean-Christophe Seznec, Julie Versapuech, Pascal Joly, Florence Corgibet, Khaled Ezzedine, Marie-Aleth Richard; and the Psychodermatology Group from the French Society of Dermatology
The prevalence of psychological disorders in patients with common skin diseases was assessed in a large representative sample of the French adult population. General health, as measured by the EQ5D score, was significantly lower if patients reported having rosacea, atopic dermatitis, urticaria, fungal infections, psoriasis or acne. The proportions of participants reporting being extremely anxious ...
Pages: 1-4
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CLINICAL REPORT
Indirect Comparison of Combined BRAF and MEK Inhibition in Melanoma Patients with Elevated Baseline Lactate Dehydrogenase
Valerie Glutsch, Teresa Amaral, Claus Garbe, Kai-Martin Thoms, Peter Mohr, Axel Hauschild, Bastian Schilling
The approval of BRAF and MEK inhibitors has significantly improved treatment outcomes for patients with BRAF-mutated metastatic melanoma. The 3 first-line targeted therapy trials have provided similar results, and thus the identification of predictive biomarkers may generate a more precise basis for clinical decision-making. Elevated baseline lactate dehydrogenase (LDH) has already been determined ...
Pages: 1-6
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SHORT COMMUNICATION
Novel CLDN1 Deletion Associated with Ichthyosis, Sclerosing Cholangitis and Acquired Alopecia
Maleha S. Alsafri, Fabienne Charbit-Henrion, Florence Lacaille, Emmanuelle Bourrat, Julie Steffann, Smail Hadj-Rabia
Abstract is missing (Short communication)
Pages: 1-2
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CLINICAL REPORT
Clinical and Ultrasonographic Profile of Adalimumab-treated Hidradenitis Suppurativa Patients: A Real-life Monocentric Experience
Andrea Chiricozzi, Giulia Giovanardi, Simone Garcovich, Dalma Malvaso, Giacomo Caldarola, Barbara Fossati, Cristina Guerriero, Clara De Simone, Ketty Peris
Ultrasonography has proven useful for diagnosis and treatment monitoring in patients with hidradenitis suppurativa. The aim of this study was to assess the clinical response to adalimumab using ultrasound findings. This prospective study collected data on demographic features, disease severity, and hidradenitis suppurativa findings from patients with hidradenitis suppurativa treated with adalimuma ...
Pages: 1-6
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SHORT COMMUNICATION
Flow Cytometry-based Detection of B-cell Lymphoproliferative Disorders in Patients with Mycosis Fungoides
Shamir Geller, Sigi Kay, Eran Ellenbogen, Tomer Goldsmith, Shoshi Bar-On, Emily Warshauer, Varda Deutsch, Eli Sprecher, Chava Perry, Ilan Goldberg
Abstract is missing (Short communication)
Pages: 1-2
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CLINICAL REPORT
Evaluating the Efficacy of Crisaborole Using the Atopic Dermatitis Severity Index and Percentage of Affected Body Surface Area
Jonathan I. Silverberg, Anna M. Tallman, William C. Ports, Robert A. Gerber, Huaming Tan, Michael A. Zielinski
Crisaborole ointment, 2%, is a nonsteroidal phosphodiesterase 4 inhibitor for the treatment of mild-to-moderate atopic dermatitis. This post hoc analysis pools results from 2 phase 3 studies (ClinicalTrials.gov, NCT02118766 [AD-301]; NCT02118792 [AD-302]) to evaluate crisaborole efficacy in patients ≥ 2 years with mild-to-moderate atopic dermatitis (per Investigator’s Static Global Assessmen ...
Pages: 1-6
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CLINICAL REPORT
Psychiatric Comorbidities in Non-psychogenic Chronic Itch, a US-based Study
Rachel Shireen Golpanian, Zoe Lipman, Kayla Fourzali, Emilie Fowler, Leigh A. Nattkemper, Yiong Huak Chan, Gil Yosipovitch
Research suggests that itch and psychiatric diseases are intimately related. In efforts to examine the prevalence of psychiatric diagnoses in patients with chronic itch not due to psychogenic causes, we conducted a retrospective chart review of 502 adult patients diagnosed with chronic itch in an outpatient dermatology clinic specializing in itch and assessed these patients for a co-existing psych ...
Pages: 1-4
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